CAJ | 학술논문

目的探讨儿童白癜风与甲状腺功能指标异常及其他免疫性疾病的关系.方法对363例白癜风儿童(男198例,女165例)和93例对照儿童(男55例,女38例)进行甲状腺功能指标的检查.结果 363例白癜风儿童中有43例(11.8%)儿童有不同程度的甲状腺功能指标的异常,93例对照组正常儿童中有4例儿童甲状腺功能指标异常,两者比较差异有统计学意义.白癜风儿童甲状腺功能指标异常发生率明显增高(P＜0.05).而43例甲状腺功能异常的白癜风儿童中,寻常型白癜风儿童为39例(13.6%),节段型白癜风儿童为4例(5.3%),寻常型比节段型白癜风儿童甲状腺功能指标异常发生率有明显增高(P＜0.05).结论儿童寻常型白癜风患者的甲状腺功能指标异常的发生率明显增高.
목적 탐토인동백전풍여갑상선공능지표이상급기타면역성질병적관계.방법 대363례백전풍인동(남198례,녀165례)화93례대조인동(남55례,녀38례)진행갑상선공능지표적검사.결과 363례백전풍인동중유43례(11.8%)인동유불동정도적갑상선공능지표적이상,93례대조조정상인동중유4례인동갑상선공능지표이상,량자비교차이유통계학의의.백전풍인동갑상선공능지표이상발생솔명현증고(P＜0.05).이43례갑상선공능이상적백전풍인동중,심상형백전풍인동위39례(13.6%),절단형백전풍인동위4례(5.3%),심상형비절단형백전풍인동갑상선공능지표이상발생솔유명현증고(P＜0.05).결론 인동심상형백전풍환자적갑상선공능지표이상적발생솔명현증고.
Objective To investigate the abnormality of parameters of thyroid function and incidence of autoimmune diseases in children with vitiligo.Methods A total of 363 children with vitiligo,including 198 males and 165 females were recruited into this study together with 93 normal human controls(55 males and 38 females).The serum levels of free tetraiodothyronine,free triiodothyronine,thyroid stimulating hormone,antithyroperoxidase antibody and thyroglobulin antibody were determined by chemiluminescent immunoassay in these subiects.Results The abnormality of parameters of thyroid function was observed in 43 out of 363(11.8%)patients affected by vitiligo and in 4 out of 93(4.3%)normal human controls;a significant difference was observed between the two groups (P＜0.05).Of the 43 patients wim abnormality of parameters of thyroid function,39 were diagnosed as vitiligo vulgaris,4 as segmental vitiligo.A significant increase Was observed in the incidence of abnormality of parameters of thyroid function in patients with vitiligo vulgaris compared with those with segmental vitiligo(P＜0.05).Conclusion There is an increase in tbe abnormality of parameters of thyroid function in children with vitiligo.