国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2009年
1期
39-40
,共2页
肺肿瘤%内皮抑素类%血清学试验%诊断
肺腫瘤%內皮抑素類%血清學試驗%診斷
폐종류%내피억소류%혈청학시험%진단
Lung neoplasms%Endostatins%Serologic tests%Diagnosis
目的 探讨肺癌患者不同临床分期、组织学类型血清内皮抑素水平,从而判断血清内皮抑素水平对肺癌的早期诊断的价值.方法 对81例肺癌患者、23例良性肺病患者和20例健康者用ELISA方法检测血清内皮抑素.对不同临床分期、病理类型血清内皮抑素的水平进行分析.结果 1)肺癌组血清内皮抑素水平(12.53±8.75)ng/mL高于良性肺病组(4.63±1.12)ng/mL和健康对照组(4.53±1.24)ng/mL,差异有统计学意义;2)Ⅰ、Ⅱ期肺癌患者血清内皮抑素的水平高于Ⅲ期,差异有统计学意义;3)肺癌患者不同病理类型血清内皮抑素水平的比较差异有统计学意义.结论 血清内皮抑素有可能成为肺癌早期诊断的参考指标.
目的 探討肺癌患者不同臨床分期、組織學類型血清內皮抑素水平,從而判斷血清內皮抑素水平對肺癌的早期診斷的價值.方法 對81例肺癌患者、23例良性肺病患者和20例健康者用ELISA方法檢測血清內皮抑素.對不同臨床分期、病理類型血清內皮抑素的水平進行分析.結果 1)肺癌組血清內皮抑素水平(12.53±8.75)ng/mL高于良性肺病組(4.63±1.12)ng/mL和健康對照組(4.53±1.24)ng/mL,差異有統計學意義;2)Ⅰ、Ⅱ期肺癌患者血清內皮抑素的水平高于Ⅲ期,差異有統計學意義;3)肺癌患者不同病理類型血清內皮抑素水平的比較差異有統計學意義.結論 血清內皮抑素有可能成為肺癌早期診斷的參攷指標.
목적 탐토폐암환자불동림상분기、조직학류형혈청내피억소수평,종이판단혈청내피억소수평대폐암적조기진단적개치.방법 대81례폐암환자、23례량성폐병환자화20례건강자용ELISA방법검측혈청내피억소.대불동림상분기、병리류형혈청내피억소적수평진행분석.결과 1)폐암조혈청내피억소수평(12.53±8.75)ng/mL고우량성폐병조(4.63±1.12)ng/mL화건강대조조(4.53±1.24)ng/mL,차이유통계학의의;2)Ⅰ、Ⅱ기폐암환자혈청내피억소적수평고우Ⅲ기,차이유통계학의의;3)폐암환자불동병리류형혈청내피억소수평적비교차이유통계학의의.결론 혈청내피억소유가능성위폐암조기진단적삼고지표.
Objective To measure the serum levels of endostatin in lung cancer patients in different stages and with histological types, and explore the clinical value of serum level in early diagnosis of lung cancer.Methods ELISA was used to detect the level of serum endostatin in 81 patients with lung cancer (lung cancer group), 23 patients with benign lung disease (benign lung disease group), 20 healthy controls (healthy control group). The serum levels of endostatin were analyzed in lung cancer patients in different stages and with histological types.Results The serum level of endostatin in lung cancer group was (2.53±8.75) ng/mL, significantly higher than that in benign lung disease group (4.63±1.12) ng/mL and healthy control group (4.53±1.24) ng/mL. In lung cancer group, the serum level of endostatin of stage Ⅰsubgroup and Ⅱsubgroup was significantly higher than that of stage Ⅲ subgroup. The differences were statistically significant. There were statistical differences of serum level of endostatin among the lung cancer patients with different histological types.Conclusion Serum endostatin might be used as an indicator of early diagnosis of lung cancer.
