国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2012年
2期
211-213
,共3页
适形放疗%非小细胞癌
適形放療%非小細胞癌
괄형방료%비소세포암
Conformal radiotherapy%Non-small-cell lung cancer
目的 探讨三维适形放疗(3DCRT)非小细胞肺癌(NSCLC)患者的疗效和副作用.方法 112例Ⅲ期NSCLC患者随机分为三维适形放疗组(治疗组)和常规放疗组(常规组)各56例.治疗组予3DCRT照射,隔日1次,每次4～8 Gy,总照射量40～ 64 Gy;常规组予常规分割照射,每周治疗5次,每次1.8～2.0 Gy,总照射量60～ 70 Gy.结果 3DCRT组有效率67.8％(CR+PR),完全缓解率32.1％(CR);常规组有效率28.6％,完全缓解率3.6％(P＜0.05).3DRCT组1年生存率为71％,常规组为48％.3DCRT组放射性肺炎、放射性食管炎和血液反应率为21％、30％和71％,均略低于常规组.结论 三维适形放疗可提高患者生存率,减轻放疗的毒副作用,治疗非小细胞肺癌比较有效.
目的 探討三維適形放療(3DCRT)非小細胞肺癌(NSCLC)患者的療效和副作用.方法 112例Ⅲ期NSCLC患者隨機分為三維適形放療組(治療組)和常規放療組(常規組)各56例.治療組予3DCRT照射,隔日1次,每次4～8 Gy,總照射量40～ 64 Gy;常規組予常規分割照射,每週治療5次,每次1.8～2.0 Gy,總照射量60～ 70 Gy.結果 3DCRT組有效率67.8％(CR+PR),完全緩解率32.1％(CR);常規組有效率28.6％,完全緩解率3.6％(P＜0.05).3DRCT組1年生存率為71％,常規組為48％.3DCRT組放射性肺炎、放射性食管炎和血液反應率為21％、30％和71％,均略低于常規組.結論 三維適形放療可提高患者生存率,減輕放療的毒副作用,治療非小細胞肺癌比較有效.
목적 탐토삼유괄형방료(3DCRT)비소세포폐암(NSCLC)환자적료효화부작용.방법 112례Ⅲ기NSCLC환자수궤분위삼유괄형방료조(치료조)화상규방료조(상규조)각56례.치료조여3DCRT조사,격일1차,매차4～8 Gy,총조사량40～ 64 Gy;상규조여상규분할조사,매주치료5차,매차1.8～2.0 Gy,총조사량60～ 70 Gy.결과 3DCRT조유효솔67.8％(CR+PR),완전완해솔32.1％(CR);상규조유효솔28.6％,완전완해솔3.6％(P＜0.05).3DRCT조1년생존솔위71％,상규조위48％.3DCRT조방사성폐염、방사성식관염화혈액반응솔위21％、30％화71％,균략저우상규조.결론 삼유괄형방료가제고환자생존솔,감경방료적독부작용,치료비소세포폐암비교유효.
Objective To investigate the results and toxic effect of three-dimensional conformal radiotherapy(3DCRT)for non-small-cell lung cancer.Methods 112 cases with stage Ⅲ non-small-cell lung cancer were randomly divided into two groups 56 in 3DRCT group and 56 in conventional group.In treatment group,patients were fractionated 3DRCT every other day and 4 ～ 8Gy every time.Total dosage were 40 ～ 70Gy.Results In 3DRCT group,the overall response rate was 67.8％(CR+PR)and complete remission rate was 32.1％(CR)while conventional group was 28.6％ and 3.6％.respectively 3DRCT group was higher(P＜ 0.05).Conclusion Three-dimensional conformal radiotherapy can increase the survival rate of patients and ease the toxic effect of chemotherapy.In a word,it' s an effective way to treat nonsmall-cell lung cancer.
