中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
7期
720-722
,共3页
韩君华%葛军%刘钧钧%刘文斌%王宝珍%史虹莉%陈书艳%CHEN shu-yan
韓君華%葛軍%劉鈞鈞%劉文斌%王寶珍%史虹莉%陳書豔%CHEN shu-yan
한군화%갈군%류균균%류문빈%왕보진%사홍리%진서염%CHEN shu-yan
年龄%正常糖耐量%血糖
年齡%正常糖耐量%血糖
년령%정상당내량%혈당
Age%Normal glucose tolerance%Blood glucose level
目的 分析不同年龄段正常糖耐量(NGT)者血糖水平及相互关系.方法 选择上海市杨浦区部分街道流行病学调研2098例30岁以上居民,根据糖耐量(OGTT)检测中空腹血糖值(FPG)和2 h血糖值(2 hPG),诊断为NGT、糖耐量低减(IGT)、空腹血糖受损(IFG)、IGT合并IFG(IGT/IFG)、糖尿病(DM),将NGT者按年龄分成5组,观察各年龄组的血糖水平,用稳态模式分析胰岛β细胞功能指数(HBCI),并对其进行统计学分析.结果 在NGT中60～69年龄组FPG值(5.17±0.48)mmol/L、糖化血红蛋白(HbA1c)(6.01±0.62)%较50～59年龄组FPG值(5.09±0.44)mmol/L、HbA1c值(5.95±0.66)%高(t值分别为2.06、2.48,P均<0.05).60～69年龄组FIG值较40～49年龄组FPG值(5.01±0.47)mmol/L高(t=2.26,P<0.01),50～59年龄组FPG值较40～49年龄组高(t=2.48,P<0.01),5组按年龄从小至大比较,空腹胰岛素(FINS)值变化无明显规律;60岁以上HBCI较60岁以下的HBCI值下降,差异有统计学意义(F值为33.75,P<0.01).结论 NGT人群随着年龄的增长,FPG、HbAlc可能增高.
目的 分析不同年齡段正常糖耐量(NGT)者血糖水平及相互關繫.方法 選擇上海市楊浦區部分街道流行病學調研2098例30歲以上居民,根據糖耐量(OGTT)檢測中空腹血糖值(FPG)和2 h血糖值(2 hPG),診斷為NGT、糖耐量低減(IGT)、空腹血糖受損(IFG)、IGT閤併IFG(IGT/IFG)、糖尿病(DM),將NGT者按年齡分成5組,觀察各年齡組的血糖水平,用穩態模式分析胰島β細胞功能指數(HBCI),併對其進行統計學分析.結果 在NGT中60～69年齡組FPG值(5.17±0.48)mmol/L、糖化血紅蛋白(HbA1c)(6.01±0.62)%較50～59年齡組FPG值(5.09±0.44)mmol/L、HbA1c值(5.95±0.66)%高(t值分彆為2.06、2.48,P均<0.05).60～69年齡組FIG值較40～49年齡組FPG值(5.01±0.47)mmol/L高(t=2.26,P<0.01),50～59年齡組FPG值較40～49年齡組高(t=2.48,P<0.01),5組按年齡從小至大比較,空腹胰島素(FINS)值變化無明顯規律;60歲以上HBCI較60歲以下的HBCI值下降,差異有統計學意義(F值為33.75,P<0.01).結論 NGT人群隨著年齡的增長,FPG、HbAlc可能增高.
목적 분석불동년령단정상당내량(NGT)자혈당수평급상호관계.방법 선택상해시양포구부분가도류행병학조연2098례30세이상거민,근거당내량(OGTT)검측중공복혈당치(FPG)화2 h혈당치(2 hPG),진단위NGT、당내량저감(IGT)、공복혈당수손(IFG)、IGT합병IFG(IGT/IFG)、당뇨병(DM),장NGT자안년령분성5조,관찰각년령조적혈당수평,용은태모식분석이도β세포공능지수(HBCI),병대기진행통계학분석.결과 재NGT중60～69년령조FPG치(5.17±0.48)mmol/L、당화혈홍단백(HbA1c)(6.01±0.62)%교50～59년령조FPG치(5.09±0.44)mmol/L、HbA1c치(5.95±0.66)%고(t치분별위2.06、2.48,P균<0.05).60～69년령조FIG치교40～49년령조FPG치(5.01±0.47)mmol/L고(t=2.26,P<0.01),50～59년령조FPG치교40～49년령조고(t=2.48,P<0.01),5조안년령종소지대비교,공복이도소(FINS)치변화무명현규률;60세이상HBCI교60세이하적HBCI치하강,차이유통계학의의(F치위33.75,P<0.01).결론 NGT인군수착년령적증장,FPG、HbAlc가능증고.
Objective To compare the glucose levels and associated factors among the normal glucose tolerance subjects with different age.Methods Totally a community-based population of 2098 residences aged above 30 years Were tested with OGTT,and classified into normal glucose tolerance group(NGT),impaired glucose tolerance group(IGT),impaired fasting glucose group(IFG),both IGT and IFG group(ICT/IFC),anddiabetes group(DM) according to fasting and 2 hours glucose level(2 hPG).The subjects in NGT group were further divided into 5 groups according to different ages.The levels of blood glucose and HBCI in different groups and subgroups were measured and analyzed statistically. Results For patients in NGT,the FPG([5.17.±0.48]mmol/L vs.[5.09±0.44]mmol/L,P<0.05)and HbA1c([6.01±0.62]%vs.[5.95±0.66]%.P<0.05)in group aged 60-69 Were higher than that in group aged 50-59.The FPG in group aged 60-69 was also higher than those in group aged 40-49([5.17±0.48]mmol/L vs.[5.00±0.47]mmol/L,P<0.01),and the FPG in group aged 50-59 Was also higher than those in group aged 40-49([5.09±0.44]mmol/L vs..[5.00±0.47]mmol/L,P<0.01).There was no correlation between age and FINS,while a tendency of decreasing HBCI could be observed along with increasing of age(F=33.75,P<0.05).Conclusion In NGT subjects,the FPG and HbA1 C inereased along with age.
