CAJ | 학술논문

目的探讨早产儿视网膜病变(ROP)的发生情况及其危险因素。方法对孕周＜36周、出生体质量＜2 000 9的244例早产儿在4周时进行眼底检查。根据ROP国际诊断分期法进行诊断和分期。结果 244例早产儿中患有不同程度ROP者49例（其中ROP Ⅰ期37例，ROPⅡ期10例，ROPⅢ期2例），ROP发生率为20.1％。孕周、出生体质量、吸氧、母亲妊娠并发症、酸中毒、呼吸暂停、PaO2的变化、机械通气及感染对ROP的发生具有明显影响（均P＜0.05）；且孕周越短、出生体质量越小，ROP发生率越高（均P＜0.05）。结论 ROP的发生与孕周、出生体质量、吸氧、母亲妊娠并发症、酸中毒、呼吸暂停、PaO2变化及感染、机械通气等因素有关，其中孕周、出生体质量、吸氧、呼吸暂停是ROP的独立危险因素。
목적 탐토조산인시망막병변(ROP)적발생정황급기위험인소。방법 대잉주＜36주、출생체질량＜2 000 9적244례조산인재4주시진행안저검사。근거ROP국제진단분기법진행진단화분기。결과 244례조산인중환유불동정도ROP자49례（기중ROP Ⅰ기37례，ROPⅡ기10례，ROPⅢ기2례），ROP발생솔위20.1％。잉주、출생체질량、흡양、모친임신병발증、산중독、호흡잠정、PaO2적변화、궤계통기급감염대ROP적발생구유명현영향（균P＜0.05）；차잉주월단、출생체질량월소，ROP발생솔월고（균P＜0.05）。결론 ROP적발생여잉주、출생체질량、흡양、모친임신병발증、산중독、호흡잠정、PaO2변화급감염、궤계통기등인소유관，기중잉주、출생체질량、흡양、호흡잠정시ROP적독립위험인소。
Objective To analyze the incidence and risk factors of retinopathy of prematurity (ROP).Methods 244 premature children 4 weeks after birth, which neonatal gestational age were ＜ 36 weeks, birth weight were ＜ 2 000g,were taken fundus examination.ROP stage at diagnosis, according to international law for the diagnosis and staging.Results 244 patients with varying degrees of premature children with ROP in 49 cases(including 37 cases of ROP Ⅰ ,ROPⅡ of the 10 cases,ROP Ⅲ 2 ,ROP rate was 20.1％.Gestational age,birth weight,oxygen,mother pregnancy complications,acidosis, apnea,PaO2 changes, mechanical ventilation and infection on the incidence of ROP had a significant effect (all P ＜ 0.05) ;and shorter gestational age, birth weight, smaller, ROP incidence higher(all P ＜ 0.05).Conclusion The incidence of ROP and gestational age, birth weight,oxygen, mother pregnancy complications, acidosis, apnea, PaO2 changes and infection, mechanical ventilation and other factors, and the gestational age, birth weight, oxygen, apnea were independent risk factors for ROP.