CAJ | 학술논문

目的探讨温度对WMO-1号液保存犬肾的影响.方法采用保存-自体移植模型,比较了不同温度条件下WMO-1号液保存犬肾24小时后的肾功能和形态学变化.结果保存肾的损害程度与保仔温度有关.15℃保存24小时不足以防止肾脏缺血损害,5～8C组术后最大血肌酐值和平均血肌酐值均显著低1～4℃组和9～12℃组,形态学变化亦较轻.结论 WMO-1号液保存犬肾的最适宜保存温度为5～8℃,保存温度过低或过高均加重肾脏损害.
목적 탐토온도대WMO-1호액보존견신적영향.방법 채용보존-자체이식모형,비교료불동온도조건하WMO-1호액보존견신24소시후적신공능화형태학변화.결과 보존신적손해정도여보자온도유관.15℃보존24소시불족이방지신장결혈손해,5～8C조술후최대혈기항치화평균혈기항치균현저저1～4℃조화9～12℃조,형태학변화역교경.결론 WMO-1호액보존견신적최괄의보존온도위5～8℃,보존온도과저혹과고균가중신장손해.
Objective To explore the effect of temperature on canine kidney preservation with WMO-1 solution.Methods Preservation-autotransplanted model was used to compare the effect of preservative temperature on the function and morphology of the canine kidneys flushed with WMO-1 solution and stored for 24 h. Results The preserved renal damage was related to the preservative temperature. Storage at 15℃ could not prevent the renal damage from ischemia. The effective preservative temperature was 1℃～ 4℃ and 9℃～12℃ . Preservation at 5℃ to 8℃ was the most suitable for canine kidney. Conclusion Lower or higher temperature might aggravate the renal injury.