国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2009年
6期
459-462
,共4页
磷脂酶A2%颈动脉疾病%动脉粥样硬化
燐脂酶A2%頸動脈疾病%動脈粥樣硬化
린지매A2%경동맥질병%동맥죽양경화
phospholipase A2%carotid disease%atherosclerosis
脂蛋白相关磷脂酶A2(lipowotein-associated phospholipase A2, Lp-PLA2)是心血管疾病的一种新型生物学标志物.它在有症状颈动脉粥样硬化斑块中的表达高于无症状颈动脉粥样硬化斑块,其产物溶血磷脂胆碱与组织氧化应激和炎症有关.另外,Lp-PLA2在颈动脉粥样硬化斑块的不稳定性差异中起着较为独特的作用.
脂蛋白相關燐脂酶A2(lipowotein-associated phospholipase A2, Lp-PLA2)是心血管疾病的一種新型生物學標誌物.它在有癥狀頸動脈粥樣硬化斑塊中的錶達高于無癥狀頸動脈粥樣硬化斑塊,其產物溶血燐脂膽堿與組織氧化應激和炎癥有關.另外,Lp-PLA2在頸動脈粥樣硬化斑塊的不穩定性差異中起著較為獨特的作用.
지단백상관린지매A2(lipowotein-associated phospholipase A2, Lp-PLA2)시심혈관질병적일충신형생물학표지물.타재유증상경동맥죽양경화반괴중적표체고우무증상경동맥죽양경화반괴,기산물용혈린지담감여조직양화응격화염증유관.령외,Lp-PLA2재경동맥죽양경화반괴적불은정성차이중기착교위독특적작용.
Lipoprotein-associated phospholipase A2(Lp-PLA2) is a novel biomarker for cardiovascular disease. Its expression in symptomatic carotid plaques is higher than that in asymptomatic ones, and its product lysophosphatidylcholine is associated with tissue oxidative stress and inflammation. In addition, Lp-PLA2 plays a more unique role in the unstable difference of carotid atherosclerotic plaques.
