中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
20期
2743-2744
,共2页
毛细支气管炎%白细胞介素6%白细胞介素8%肿瘤坏死因子α
毛細支氣管炎%白細胞介素6%白細胞介素8%腫瘤壞死因子α
모세지기관염%백세포개소6%백세포개소8%종류배사인자α
Bronchiolitis%IL-6%IL-8%TNF-α
目的 探讨毛细支气管炎患儿血清白细胞介素6(IL-6)、白细胞介素8(IL-8)和肿瘤坏死因子α(TNF-α)在毛细支气管炎患儿发病中的作用。方法 收集50例毛细支气管炎患儿，检测其急性期与恢复期血清IL-6、IL-8和TNF-α水平，另选择20例健康儿童作为健康对照组进行比较。结果 患儿在急性期血清IL-6、IL-8和TNF-α水平均明显高于恢复期和对照组（均P＜0.05），患儿恢复期血清IL-6、IL-8和TNF-α水平与对照组比较差异均无统计学意义（均P＞0.05）。结论 血清IL-6、IL-8与TNF-α可能在毛细支气管炎发病过程中起重要作用，它们可能成为预测毛细支气管炎病情的重要指标。
目的 探討毛細支氣管炎患兒血清白細胞介素6(IL-6)、白細胞介素8(IL-8)和腫瘤壞死因子α(TNF-α)在毛細支氣管炎患兒髮病中的作用。方法 收集50例毛細支氣管炎患兒，檢測其急性期與恢複期血清IL-6、IL-8和TNF-α水平，另選擇20例健康兒童作為健康對照組進行比較。結果 患兒在急性期血清IL-6、IL-8和TNF-α水平均明顯高于恢複期和對照組（均P＜0.05），患兒恢複期血清IL-6、IL-8和TNF-α水平與對照組比較差異均無統計學意義（均P＞0.05）。結論 血清IL-6、IL-8與TNF-α可能在毛細支氣管炎髮病過程中起重要作用，它們可能成為預測毛細支氣管炎病情的重要指標。
목적 탐토모세지기관염환인혈청백세포개소6(IL-6)、백세포개소8(IL-8)화종류배사인자α(TNF-α)재모세지기관염환인발병중적작용。방법 수집50례모세지기관염환인，검측기급성기여회복기혈청IL-6、IL-8화TNF-α수평，령선택20례건강인동작위건강대조조진행비교。결과 환인재급성기혈청IL-6、IL-8화TNF-α수평균명현고우회복기화대조조（균P＜0.05），환인회복기혈청IL-6、IL-8화TNF-α수평여대조조비교차이균무통계학의의（균P＞0.05）。결론 혈청IL-6、IL-8여TNF-α가능재모세지기관염발병과정중기중요작용，타문가능성위예측모세지기관염병정적중요지표。
Objective To explore the roles of IL-6, IL-8 and TNF-α in infants with bronchiolitis.Methods The levels of serum IL-6, IL-8 and TNF-αt were detected in 50 infants with broncHoliris during convalescence stage and acute stage, and compared with those of 20 healthy children as control group.Results The serum levels of IL-6, IL-8 and TNF-α during acute stage were significandy increased in comparison with those during convalescence stage(all P ＜0.05) ,but there was no significant difference between convalescence stage and normal control group(all P ＞ 0.05).Conclusion The cytokines of IL-6, IL-8 and TNF-α maybe play an important role in the pathogeny of bronchiolitis.The serum levels of IL-6,IL-8 and TNF-α could be used to predict the degree of bronchiolitis in infants.
