中华糖尿病杂志
中華糖尿病雜誌
중화당뇨병잡지
CHINES JOURNAL OF DLABETES MELLITUS
2012年
2期
101-105
,共5页
林晖%王宾友%刘雅%易延静%黄晓波%欧阳凌云
林暉%王賓友%劉雅%易延靜%黃曉波%歐暘凌雲
림휘%왕빈우%류아%역연정%황효파%구양릉운
高血压%血脂异常%高血糖症%高血压前期
高血壓%血脂異常%高血糖癥%高血壓前期
고혈압%혈지이상%고혈당증%고혈압전기
Hypertension%Dyslipidemias%Hyperglycemia%Prehypertension
目的 探讨成都地区社区居民高血压前期和糖脂代谢紊乱之间的关系.方法 2008年4月至11月应用分层整群抽样方法,选取成都市3个社区的40岁及以上居民,进行问卷调查和体格检查,给予口服葡萄糖耐量试验,并检测血糖、血脂等生化指标.在5123名40岁及以上中老年人群中,正常血压者1486名,平均年龄(52±10)岁；高血压前期者1636名,平均年龄(55±10)岁.比较两组人群的糖脂代谢情况,并进一步分析高血压前期与相关因素的关系.计量资料以均数±标准差表示,两组间比较采用t检验,计数资料比较采用x2检验,相关因素分析采用logistic回归分析.结果 成都地区中老年人群高血压前期总体患病率为31.93％,标化患病率为32.70％,其中男性为35.56％,女性为29.69％.高血压前期组/正常血压组在单纯空腹血糖受损、单纯糖耐量异常、空腹血糖受损合并糖耐量异常以及糖尿病的患病率分别为3.42％/2.22％、18.46％/14.47％、2.69％/1.55％和15.71％/8.41％,两组间比较差异均有统计学意义(x2=4.064、8.978、4.833、38.613,均P＜0.05).高血压前期组/正常血压组在高胆固醇血症、高甘油三酯血症、高低密度脂蛋白胆固醇( LDL-C)和低高密度脂蛋白胆固醇(HDL-C)的患病率分别为5.38％/3.30％、17.11％/9.62％、2.69％/1.68％和11.74％/6.93％,两组间比较差异均有统计学意义(x2 =8.041、37.313、4.219、21.009,均P＜0.05).logistic回归分析显示,年龄、性别、BMI、腰臀比、餐后血糖、总胆固醇、甘油三酯和HDL-C均与高血压前期相关(OR=1.03、0.60、1.10、6.92、1.04、1.19、1.10、0.68,均P＜0.05),其中女性和HDL-C升高是高血压前期的保护因素,年龄和性别是不可控因素.结论 成都地区社区中老年人群高血压前期的患病率高,中老年高血压前期人群更易合并糖尿病和血脂紊乱,高血压前期与糖脂代谢关系密切.
目的 探討成都地區社區居民高血壓前期和糖脂代謝紊亂之間的關繫.方法 2008年4月至11月應用分層整群抽樣方法,選取成都市3箇社區的40歲及以上居民,進行問捲調查和體格檢查,給予口服葡萄糖耐量試驗,併檢測血糖、血脂等生化指標.在5123名40歲及以上中老年人群中,正常血壓者1486名,平均年齡(52±10)歲；高血壓前期者1636名,平均年齡(55±10)歲.比較兩組人群的糖脂代謝情況,併進一步分析高血壓前期與相關因素的關繫.計量資料以均數±標準差錶示,兩組間比較採用t檢驗,計數資料比較採用x2檢驗,相關因素分析採用logistic迴歸分析.結果 成都地區中老年人群高血壓前期總體患病率為31.93％,標化患病率為32.70％,其中男性為35.56％,女性為29.69％.高血壓前期組/正常血壓組在單純空腹血糖受損、單純糖耐量異常、空腹血糖受損閤併糖耐量異常以及糖尿病的患病率分彆為3.42％/2.22％、18.46％/14.47％、2.69％/1.55％和15.71％/8.41％,兩組間比較差異均有統計學意義(x2=4.064、8.978、4.833、38.613,均P＜0.05).高血壓前期組/正常血壓組在高膽固醇血癥、高甘油三酯血癥、高低密度脂蛋白膽固醇( LDL-C)和低高密度脂蛋白膽固醇(HDL-C)的患病率分彆為5.38％/3.30％、17.11％/9.62％、2.69％/1.68％和11.74％/6.93％,兩組間比較差異均有統計學意義(x2 =8.041、37.313、4.219、21.009,均P＜0.05).logistic迴歸分析顯示,年齡、性彆、BMI、腰臀比、餐後血糖、總膽固醇、甘油三酯和HDL-C均與高血壓前期相關(OR=1.03、0.60、1.10、6.92、1.04、1.19、1.10、0.68,均P＜0.05),其中女性和HDL-C升高是高血壓前期的保護因素,年齡和性彆是不可控因素.結論 成都地區社區中老年人群高血壓前期的患病率高,中老年高血壓前期人群更易閤併糖尿病和血脂紊亂,高血壓前期與糖脂代謝關繫密切.
목적 탐토성도지구사구거민고혈압전기화당지대사문란지간적관계.방법 2008년4월지11월응용분층정군추양방법,선취성도시3개사구적40세급이상거민,진행문권조사화체격검사,급여구복포도당내량시험,병검측혈당、혈지등생화지표.재5123명40세급이상중노년인군중,정상혈압자1486명,평균년령(52±10)세；고혈압전기자1636명,평균년령(55±10)세.비교량조인군적당지대사정황,병진일보분석고혈압전기여상관인소적관계.계량자료이균수±표준차표시,량조간비교채용t검험,계수자료비교채용x2검험,상관인소분석채용logistic회귀분석.결과 성도지구중노년인군고혈압전기총체환병솔위31.93％,표화환병솔위32.70％,기중남성위35.56％,녀성위29.69％.고혈압전기조/정상혈압조재단순공복혈당수손、단순당내량이상、공복혈당수손합병당내량이상이급당뇨병적환병솔분별위3.42％/2.22％、18.46％/14.47％、2.69％/1.55％화15.71％/8.41％,량조간비교차이균유통계학의의(x2=4.064、8.978、4.833、38.613,균P＜0.05).고혈압전기조/정상혈압조재고담고순혈증、고감유삼지혈증、고저밀도지단백담고순( LDL-C)화저고밀도지단백담고순(HDL-C)적환병솔분별위5.38％/3.30％、17.11％/9.62％、2.69％/1.68％화11.74％/6.93％,량조간비교차이균유통계학의의(x2 =8.041、37.313、4.219、21.009,균P＜0.05).logistic회귀분석현시,년령、성별、BMI、요둔비、찬후혈당、총담고순、감유삼지화HDL-C균여고혈압전기상관(OR=1.03、0.60、1.10、6.92、1.04、1.19、1.10、0.68,균P＜0.05),기중녀성화HDL-C승고시고혈압전기적보호인소,년령화성별시불가공인소.결론 성도지구사구중노년인군고혈압전기적환병솔고,중노년고혈압전기인군경역합병당뇨병화혈지문란,고혈압전기여당지대사관계밀절.
Objective To study the relationship between the prehypertension and disorders of glucose and lipid metabolism among the community residents in Chengdu area.Methods A cross-sectional population-based survey for chronic diseases in Chengdu was performed from April to November in 2008.Using cluster random sampling method, three communities were selected in Chengdu area. All the participants completed a detailed questionnaire and underwent anthropometric measurements.A total of 1486 normotensive subjects and 1636 prehypertensive subjects among the 5123 individuals aged 40 years and above were included in this study. The glucose and lipid metabolism profiles in normotensive group and prehypertension group were determined and compared. The relation between prehypertension and other related clinicopathological factors was also investigated.Chi-squared tests for categorical variables,t-tests for continuous variables and logistic regression analysis for related risk factors were performed in this study.Results The total prevalence of prehypertension among the community residents aged 40 years and over in Chengdu area was 31.93％,the standard prevalence was 32.70％,it was 35.56％ in male and 29.69％ in female.The prevalence of isolated impaired fasting glucose,isolated impaired glucose tolerance,impaired fasting glucose combined impaired glucose tolerance and diabetes were 3.42％/2.22％,18.46％/14.47％,2.69％/1.55％ and 15.71％/8.41％ in prehypertensive/ normotensive subjects respectively; there were significant differences in all the above-mentioned four parameters between the two groups ( x2 =4.064,8.978,4.833,38.613,respectively; all P ＜ 0.05 ). The prevalence of hypercholesterolemia,hypertriglyceridemia,high low density lipoprotein-cholesterol (LDL-C) and low high density lipoproteincholesterol (HDL-C) were 5.38％/3.30％,17.11％/9.62％,2.69％/1.68％ and 11.74％/6.93％ in prehypertensive/normotensive subjects respectively; there were significant differences in all the abovementioned four parameters between the two groups (x2 =8.041,37.313,4.219,21.009,all P ＜ 0.05 ).Logistic regression analysis showed that age, gender, body mass index,waist to hip ratio, elevated postprandial blood glucose, elevated triglycerides, total cholesterol and HDL-C were correlated with prehypertension( OR =1.03,0.60,1.10,6.92,1.04,1.10,1.19,0.68,all P ＜ 0.05 ).Female and elevated HDL-C were negatively correlated with prehypertension ( all P ＜ 0.05).Age and gender were nonmodifiable factors.Conclusions Prehypertension is highly prevalent among middle-aged and elderly in the communities in Chengdu area.The prehypertensive subjects are more susceptible to diabetes and dyslipidemia.
