CAJ | 학술논문

目的探讨黄芪注射液治疗早产儿脑室周围白质软化的临床疗效.方法将2006年10月至2010年9月泰山医学院附属聊城市第二人民医院新生儿病房收治的85例确诊为脑室周围白质软化的早产儿随机分为两组.Ⅰ组(对照组)42例,采用保暖、吸氧、控制感染、纠正酸碱及电解质紊乱,维持正常血糖、血压、血气等常规治疗;Ⅱ组43例,在常规治疗基础上加用黄芪注射液静脉注射.定期观察和随诊颅脑B超的变化,进行统计学分析.结果 ①黄芪注射液治疗组治疗有效率优于对照组,两组比较差异有统计学意义(P＜0.05);②分别于校正胎龄40、41周进行2次新生儿神经行为(NBNA)评分,黄芪注射液治疗组明显优于对照组,差异有统计学意义(P＜0.01).结论黄芪注射液治疗早产儿脑室周围白质软化疗效显著,可改善预后.
목적 탐토황기주사액치료조산인뇌실주위백질연화적림상료효.방법 장2006년10월지2010년9월태산의학원부속료성시제이인민의원신생인병방수치적85례학진위뇌실주위백질연화적조산인수궤분위량조.Ⅰ조(대조조)42례,채용보난、흡양、공제감염、규정산감급전해질문란,유지정상혈당、혈압、혈기등상규치료;Ⅱ조43례,재상규치료기출상가용황기주사액정맥주사.정기관찰화수진로뇌B초적변화,진행통계학분석.결과 ①황기주사액치료조치료유효솔우우대조조,량조비교차이유통계학의의(P＜0.05);②분별우교정태령40、41주진행2차신생인신경행위(NBNA)평분,황기주사액치료조명현우우대조조,차이유통계학의의(P＜0.01).결론 황기주사액치료조산인뇌실주위백질연화료효현저,가개선예후.
Objective To investigate the clinical effects of astragalus injection in treating periventricular leukomalacia in premature infants.Methods Eighty-five premature infants with periventricular leukomalacia who were in newborn intensive care uint of our hospital from October 2006 to September 2010 were randomly divided into the control group(42 cases)and astragalus injection group (43 cases).The cases in control group(group Ⅰ)were given routine treatment.The cases in astragalus injection group(group Ⅱ)were given astragalus injection on the base of the control group.The differences of B ultrasonic were observed and were analyzed by statistics.Results ①The effective rate in astragalus injection group was obviously higher than that in control group.There were significant difference between the two groups by statistics(P ＜ 0.05).②Neonatal behavioral neurological assessment(NBNA)was evaluated when age of the newborns were 40 weeks and 41 weeks.There was obvious difference between the two groups(P ＜ 0.01).Conclusions Astragalus injection have obvious effect on treating periventricular leukomalacia in premature infants and can improve the prognosis.