中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2011年
9期
759-763
,共5页
超声心动描记术,实时三维%代谢综合征X%心室功能,左%脂联素
超聲心動描記術,實時三維%代謝綜閤徵X%心室功能,左%脂聯素
초성심동묘기술,실시삼유%대사종합정X%심실공능,좌%지련소
Echocardiography,real-time three-dimensional%Metabolic syndrome X%Ventricular function,left%Adiponectin
目的 应用实时三维超声评价代谢综合征(MS)患者左心功能的早期改变，分析MS患者血清脂联素变化的临床价值。方法 依据国际糖尿病联盟(IDF)诊断MS的标准将受试者分为MS组和对照组，均进行二维及实时三维超声心动图检查，同时进行血清脂联素的测定。结果 MS组的17节段容积-时间曲线参数指标-左室16、12节段达最小收缩容积的时间标准差(Tmsv16-SD、Tmsv12-SD)、最大差值(Tmsv 16-Dif、Tmsv12-Dif)及心率校正值(Tmsv16-SD％，Tmsv12-SD％,Tmsv16-Dif％，Tmsv12-Dif％)与正常对照组比较，差别均有统计学意义(P＜0.05);左室部分室壁局部射血分数、心搏量及局-整射血分数、局-整心搏量及血清脂联素水平均较对照组降低，差异有统计学意义(P＜0.05);二尖瓣口前向血流频谱E/A及二尖瓣环组织多普勒频谱E/E’均降低，差异有统计学意义(P＜0.05)。血清脂联素与二尖瓣口前向血流频谱E/A值、二尖瓣环组织多普勒频谱E'/A’值呈正相关(r 分别为0.368,0.493,P＜0.05);与E/E’值呈负相关(r=-0.347,P＜0.05)。结论实时三维超声心动图能快速准确地评价MS患者的左室收缩、舒张功能改变及节段收缩的同步性;脂联素与左室整体舒张功能改变存在良好的相关性，有望成为预测左室舒张功能早期改变的新指标。
目的 應用實時三維超聲評價代謝綜閤徵(MS)患者左心功能的早期改變，分析MS患者血清脂聯素變化的臨床價值。方法 依據國際糖尿病聯盟(IDF)診斷MS的標準將受試者分為MS組和對照組，均進行二維及實時三維超聲心動圖檢查，同時進行血清脂聯素的測定。結果 MS組的17節段容積-時間麯線參數指標-左室16、12節段達最小收縮容積的時間標準差(Tmsv16-SD、Tmsv12-SD)、最大差值(Tmsv 16-Dif、Tmsv12-Dif)及心率校正值(Tmsv16-SD％，Tmsv12-SD％,Tmsv16-Dif％，Tmsv12-Dif％)與正常對照組比較，差彆均有統計學意義(P＜0.05);左室部分室壁跼部射血分數、心搏量及跼-整射血分數、跼-整心搏量及血清脂聯素水平均較對照組降低，差異有統計學意義(P＜0.05);二尖瓣口前嚮血流頻譜E/A及二尖瓣環組織多普勒頻譜E/E’均降低，差異有統計學意義(P＜0.05)。血清脂聯素與二尖瓣口前嚮血流頻譜E/A值、二尖瓣環組織多普勒頻譜E'/A’值呈正相關(r 分彆為0.368,0.493,P＜0.05);與E/E’值呈負相關(r=-0.347,P＜0.05)。結論實時三維超聲心動圖能快速準確地評價MS患者的左室收縮、舒張功能改變及節段收縮的同步性;脂聯素與左室整體舒張功能改變存在良好的相關性，有望成為預測左室舒張功能早期改變的新指標。
목적 응용실시삼유초성평개대사종합정(MS)환자좌심공능적조기개변，분석MS환자혈청지련소변화적림상개치。방법 의거국제당뇨병련맹(IDF)진단MS적표준장수시자분위MS조화대조조，균진행이유급실시삼유초성심동도검사，동시진행혈청지련소적측정。결과 MS조적17절단용적-시간곡선삼수지표-좌실16、12절단체최소수축용적적시간표준차(Tmsv16-SD、Tmsv12-SD)、최대차치(Tmsv 16-Dif、Tmsv12-Dif)급심솔교정치(Tmsv16-SD％，Tmsv12-SD％,Tmsv16-Dif％，Tmsv12-Dif％)여정상대조조비교，차별균유통계학의의(P＜0.05);좌실부분실벽국부사혈분수、심박량급국-정사혈분수、국-정심박량급혈청지련소수평균교대조조강저，차이유통계학의의(P＜0.05);이첨판구전향혈류빈보E/A급이첨판배조직다보륵빈보E/E’균강저，차이유통계학의의(P＜0.05)。혈청지련소여이첨판구전향혈류빈보E/A치、이첨판배조직다보륵빈보E'/A’치정정상관(r 분별위0.368,0.493,P＜0.05);여E/E’치정부상관(r=-0.347,P＜0.05)。결론실시삼유초성심동도능쾌속준학지평개MS환자적좌실수축、서장공능개변급절단수축적동보성;지련소여좌실정체서장공능개변존재량호적상관성，유망성위예측좌실서장공능조기개변적신지표。
Objective To evaluate the change of left ventricular(LV) function by real-time three dimensional echocardiography(RT-3DE) and to explore the clinical value of change of serum adiponectin level in patients with metabolic syndrome (MS).Methods One hundred and twenty patients were divided into MS group and control group according to the diagnostic standard of the nternational Diabetes Federation.Transthorasic 2D ultrasound and RT-3DE examination were performed in all study objects, and serum adiponectin levels were measured.Results Parameter index [including Tmsv16-SD, Tmsv12-SD,Tmsv16- Dif, Tmsv12-Dif, Tmsv16-SD (％), Tmsv 12-SD (％), Tmsv16-Dif (％), Tmsv12-Dif (％)] of 17segment time to minimal systolic volume in MS group was more than that in control group (all P ＜0.05).Some regional systolic index of LV and serum adiponectin level were less than that in control group (all P ＜0.05).Compared with the control group, E/E' was lower (P ＜ 0.05).There were significant relations between serum adiponectin level and E/A of mitral valves, E'/A' of mitral annulus and E/E'(r = 0.368,0.493,and -0.347 respectively, P ＜0.05).Conclusions RT-3DE can rapidly evaluate LV systolic and diastolic synchrony in MS patients.E/E' show an excellent correlation with serum adiponectin level,and it may be a new promising method for routine evaluation of LV diastolic function.
