CAJ | 학술논문

在肿瘤发生发展的过程中,机体免疫系统与肿瘤细胞相互作用,相互编辑.免疫系统的监视作用可清除肿瘤或抑制肿瘤的发生发展,同时免疫系统又可对肿瘤细胞进行重塑,使肿瘤发生免疫逃逸.而肿瘤可诱发机体抗肿瘤的固有及获得性免疫应答,同时也可改变免疫系统的抗肿瘤效应.了解肿瘤免疫编辑的相关研究进展可以为肿瘤防治提供参考.
재종류발생발전적과정중,궤체면역계통여종류세포상호작용,상호편집.면역계통적감시작용가청제종류혹억제종류적발생발전,동시면역계통우가대종류세포진행중소,사종류발생면역도일.이종류가유발궤체항종류적고유급획득성면역응답,동시야가개변면역계통적항종류효응.료해종류면역편집적상관연구진전가이위종류방치제공삼고.
During the development of tumors, interaction and editing occur between immune system and tumor cells. Tumor cells could be eradicated or tumor developments could be inhibited because of the surveillance role of immune system, while immune escape may occur for tumor cells remodeled by immune system. Tumors can induce innate and adaptive immune responses as well alter the anti-tumor effect of the immune system. This re-view will summarizes the development of researches in cancer immunoediting in order to insights references for tumor therapy.