中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2011年
4期
282-285
,共4页
杨娅玲%江睿%何太雯%卢洪洲
楊婭玲%江睿%何太雯%盧洪洲
양아령%강예%하태문%로홍주
获得性免疫缺陷综合症/艾滋病病毒感染%视网膜脱离%玻璃体视网膜手术
穫得性免疫缺陷綜閤癥/艾滋病病毒感染%視網膜脫離%玻璃體視網膜手術
획득성면역결함종합증/애자병병독감염%시망막탈리%파리체시망막수술
Acquired immunodeficiency syndrome/HIV infection%Retinal detachment%Vitroretinalsurgery
目的 探讨获得性免疫缺陷综合征(AIDS)/艾滋病病毒(HIV)感染合并视网膜脱离(RD)的临床特点、药物及手术治疗.方法 回顾11例(16眼)AIDS/HIV感染患者RD的实验室检查和临床诊治资料,分析其病因、与细胞免疫的关系、RD发生的高危因素、治疗方法及治疗效果的影响因素.6例(6眼)做了玻璃体视网膜手术.结果 13眼孔源性RD由病毒性视网膜炎及可疑病毒性视网膜炎引起,2眼RD由梅毒性葡萄膜炎引起,1眼为原发性孔源性视网膜脱离;发病时,6例CD4+T淋巴细胞计数低于100个/μL,3例CD4+T淋巴细胞计数高于200个/μL;未手术眼视力无改变,手术眼术后视力有不同程度提高,病程短及单纯性孔源性网脱眼术后矫正视力好于病程长及感染性视网膜炎导致的网脱眼.结论 病毒性视网膜炎是CD4+T淋巴细胞计数较低的AIDS患者发生孔源性RD的主要病因,原发性孔源性RD及非病毒感染葡萄膜视网膜炎是CD4+T淋巴细胞计数较高的AIDS/HIV感染患者RD的主要病因.CD4+T淋巴细胞计数较低是RD的高危因素;玻璃体视网膜手术是视网膜解剖复位、改善视力的首选治疗方法.RD的病因、病程及病情严重程度是影响手术后视力的因素.
目的 探討穫得性免疫缺陷綜閤徵(AIDS)/艾滋病病毒(HIV)感染閤併視網膜脫離(RD)的臨床特點、藥物及手術治療.方法 迴顧11例(16眼)AIDS/HIV感染患者RD的實驗室檢查和臨床診治資料,分析其病因、與細胞免疫的關繫、RD髮生的高危因素、治療方法及治療效果的影響因素.6例(6眼)做瞭玻璃體視網膜手術.結果 13眼孔源性RD由病毒性視網膜炎及可疑病毒性視網膜炎引起,2眼RD由梅毒性葡萄膜炎引起,1眼為原髮性孔源性視網膜脫離;髮病時,6例CD4+T淋巴細胞計數低于100箇/μL,3例CD4+T淋巴細胞計數高于200箇/μL;未手術眼視力無改變,手術眼術後視力有不同程度提高,病程短及單純性孔源性網脫眼術後矯正視力好于病程長及感染性視網膜炎導緻的網脫眼.結論 病毒性視網膜炎是CD4+T淋巴細胞計數較低的AIDS患者髮生孔源性RD的主要病因,原髮性孔源性RD及非病毒感染葡萄膜視網膜炎是CD4+T淋巴細胞計數較高的AIDS/HIV感染患者RD的主要病因.CD4+T淋巴細胞計數較低是RD的高危因素;玻璃體視網膜手術是視網膜解剖複位、改善視力的首選治療方法.RD的病因、病程及病情嚴重程度是影響手術後視力的因素.
목적 탐토획득성면역결함종합정(AIDS)/애자병병독(HIV)감염합병시망막탈리(RD)적림상특점、약물급수술치료.방법 회고11례(16안)AIDS/HIV감염환자RD적실험실검사화림상진치자료,분석기병인、여세포면역적관계、RD발생적고위인소、치료방법급치료효과적영향인소.6례(6안)주료파리체시망막수술.결과 13안공원성RD유병독성시망막염급가의병독성시망막염인기,2안RD유매독성포도막염인기,1안위원발성공원성시망막탈리;발병시,6례CD4+T림파세포계수저우100개/μL,3례CD4+T림파세포계수고우200개/μL;미수술안시력무개변,수술안술후시력유불동정도제고,병정단급단순성공원성망탈안술후교정시력호우병정장급감염성시망막염도치적망탈안.결론 병독성시망막염시CD4+T림파세포계수교저적AIDS환자발생공원성RD적주요병인,원발성공원성RD급비병독감염포도막시망막염시CD4+T림파세포계수교고적AIDS/HIV감염환자RD적주요병인.CD4+T림파세포계수교저시RD적고위인소;파리체시망막수술시시망막해부복위、개선시력적수선치료방법.RD적병인、병정급병정엄중정도시영향수술후시력적인소.
Objective To explore the clinical characteristics and treatment of retinal detachment (RD)in acquired immunodeficiency syndrome(AIDS)/HIV infection patients.Methods The clinical and laboratory data of 11 AIDS/HIV infected patients(16 eyes)with RD were reviewed.The etiology、risk factors and treatment of RD were analyzed retrospectively and 6 cases ( 6 eyes)in which underwent vitreoretinal surgery.Results 13 eyes were caused by vires retinitis and suspected virus retinitis,2 eyes by syphilitic chorioretinitis,one eye by primary rhegmatogenous retinal detachment.The CD4+T lymphocyte count in 6 patients were less than 100 cell/μL and more than 200 cell/μL in 3 patients when RD occured;The visual acuity of eyes that unaccepted surgery unchanged,increased in operated eyes.The corrected visual acuity of rhegmatogenous RD with shorter duration was better than that with longer duration or infectious retinitis.Conclusion The main reason of RD in AIDS/HIV infection patients with lower CD4+T lymphocyte count was virus retinitis.That with higher CD4+T lymphocyte count was primary rhegmatogenous RD and non-virus retinal infection.Low CD4+T lymphocyte Was a risk factor.Surgery was the first choice for retinal anatomical reattachment and visual acuity improvement.The etiology、duration and the severity of RD affected the visional acuity of operated eyes.
