CAJ | 학술논문

目的探讨影响脑膜瘤患者术后近期预后的相关因素.方法回顾性研究哈尔滨医科大学附属第一医院自1999年1月至2006年12月收治的953例良性脑膜瘤患者,用出院时患者的生活质量评分(KPS)来评价预后,对患者的年龄,肿瘤部位,肿瘤大小,术前伴有高血压、糖尿病、心脏病及脑梗死,肿瘤切除级别,术中出血量及合并失血性休克、脑膨出等11个因素行单因素x2检验和多因素Logistic回归模型分析,探讨影响脑膜瘤术后患者近期预后的相关因素.结果患者年龄、肿瘤部位及大小、术前伴有脑梗死、肿瘤切除级别、术中出血量及合并失血性休克预后差异有统计学意义(P＜0.05);且肿瘤大小、术前伴有脑梗死、切除级别、术中合并失血性休克是影响预后的独立危险因素.而术前伴有高血压、心脏病、糖尿病及术中合并脑膨出与预后无关(P＞0.05).结论患者的年龄、肿瘤的部位和术前合并症都可能影响患者的预后,但肿瘤大小、术前伴有脑梗死、切除级别、术中合并失血性休克是影响预后的独立危险因素.
목적 탐토영향뇌막류환자술후근기예후적상관인소.방법 회고성연구합이빈의과대학부속제일의원자1999년1월지2006년12월수치적953례량성뇌막류환자,용출원시환자적생활질량평분(KPS)래평개예후,대환자적년령,종류부위,종류대소,술전반유고혈압、당뇨병、심장병급뇌경사,종류절제급별,술중출혈량급합병실혈성휴극、뇌팽출등11개인소행단인소x2검험화다인소Logistic회귀모형분석,탐토영향뇌막류술후환자근기예후적상관인소.결과 환자년령、종류부위급대소、술전반유뇌경사、종류절제급별、술중출혈량급합병실혈성휴극예후차이유통계학의의(P＜0.05);차종류대소、술전반유뇌경사、절제급별、술중합병실혈성휴극시영향예후적독립위험인소.이술전반유고혈압、심장병、당뇨병급술중합병뇌팽출여예후무관(P＞0.05).결론 환자적년령、종류적부위화술전합병증도가능영향환자적예후,단종류대소、술전반유뇌경사、절제급별、술중합병실혈성휴극시영향예후적독립위험인소.
Objective To study the related factors of early post-operative prognosis of meningiomas. Methods The clinical data of 953 patients with meningiomas were recorded and statistically analyzed withx2 test of single factor and logistic regression model of multivariate factors. Patient age; tumor size; tumor location; pre-operative complication of patients such as hypertension, diabetes, heart disease and cerebral infarction; the extent of tumor resection; hemorrhagic shock; blood loss or hemorrhagic shock and brain swelling intra-operatively were taken as variables. The prognosis was evaluated by postoperative Karnofsky performance scale. Results The prognosis was significantly correlated with the patient age, tumor size, tumor location, preoperative cerebral infarction, the extent of tumor resection, blood loss and hemorrhagic shock intra-operatively ( P ＜ 0. 05 ) . Such factors as tumor size, preoperative cerebral infarction, the extent of tumor resection (Simpson's scale) and intra-operative hemorrhagic shock were independent risk factors of prognosis for meningiomas. Other factors, such as hypertension, diabetes and heart disease, were unrelated with the prognosis of meningiomas ( P ＞ 0. 05 ). Conclusion Patient age,tumor location and pre-operative complications of patients maybe affect the early postoperative prognosis of meningiomas. But such factors as tumor size, preoperative cerebral infarction, the extent of tumor resection and intra-operative hemorrhagic shock are independent risk factors for the post-operative prognosis of meningiomas.