中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
9期
1150-1152
,共3页
崔志超%王宇%赵亚婷%胡继卫%马杰%张景华%胡万宁
崔誌超%王宇%趙亞婷%鬍繼衛%馬傑%張景華%鬍萬寧
최지초%왕우%조아정%호계위%마걸%장경화%호만저
乳腺癌%前哨淋巴结%前哨淋巴结活检%99Tcm硫胶体%美蓝
乳腺癌%前哨淋巴結%前哨淋巴結活檢%99Tcm硫膠體%美藍
유선암%전초림파결%전초림파결활검%99Tcm류효체%미람
Breast cancer%Sentinel lymph node%Sentinel lymph node biopsy%99Tcm-sulfur colloid%Methylene blue
目的 探讨99Tcm硫胶体(99Tcm-sulfur colloid,99Tcm-SC)联合美蓝在早期乳腺癌前哨淋巴结活检(SLNB)中的可行性、准确性及临床应用价值.方法 采用99Tcm-SC联合美蓝对76例T1～ 2N0M0乳腺癌患者进行SLNB,将切除的前哨淋巴结行病理检查了解其符合率,探讨联合法在早期乳腺癌SLNB中的临床应用价值.结果 成功确定患者前哨淋巴结76例,7例前哨淋巴结病理检测阳性并行腋窝淋巴结清扫,99Tcm-SC灵敏度为85.7％ (6/7),准确性为98.7％( 75/76),假阴性率为14.3％( 1/7),美蓝法灵敏度为71.4％ (5/7),准确性为97.4％ (74/76),假阴性率为28.6％ (2/7).联合法灵敏度、准确性为100.0％(7/7,76/76),假阳性率为0(0/7).结论 99Tcm-SC联合美蓝可明显降低早期乳腺癌SLNB的假阴性率.
目的 探討99Tcm硫膠體(99Tcm-sulfur colloid,99Tcm-SC)聯閤美藍在早期乳腺癌前哨淋巴結活檢(SLNB)中的可行性、準確性及臨床應用價值.方法 採用99Tcm-SC聯閤美藍對76例T1～ 2N0M0乳腺癌患者進行SLNB,將切除的前哨淋巴結行病理檢查瞭解其符閤率,探討聯閤法在早期乳腺癌SLNB中的臨床應用價值.結果 成功確定患者前哨淋巴結76例,7例前哨淋巴結病理檢測暘性併行腋窩淋巴結清掃,99Tcm-SC靈敏度為85.7％ (6/7),準確性為98.7％( 75/76),假陰性率為14.3％( 1/7),美藍法靈敏度為71.4％ (5/7),準確性為97.4％ (74/76),假陰性率為28.6％ (2/7).聯閤法靈敏度、準確性為100.0％(7/7,76/76),假暘性率為0(0/7).結論 99Tcm-SC聯閤美藍可明顯降低早期乳腺癌SLNB的假陰性率.
목적 탐토99Tcm류효체(99Tcm-sulfur colloid,99Tcm-SC)연합미람재조기유선암전초림파결활검(SLNB)중적가행성、준학성급림상응용개치.방법 채용99Tcm-SC연합미람대76례T1～ 2N0M0유선암환자진행SLNB,장절제적전초림파결행병리검사료해기부합솔,탐토연합법재조기유선암SLNB중적림상응용개치.결과 성공학정환자전초림파결76례,7례전초림파결병리검측양성병행액와림파결청소,99Tcm-SC령민도위85.7％ (6/7),준학성위98.7％( 75/76),가음성솔위14.3％( 1/7),미람법령민도위71.4％ (5/7),준학성위97.4％ (74/76),가음성솔위28.6％ (2/7).연합법령민도、준학성위100.0％(7/7,76/76),가양성솔위0(0/7).결론 99Tcm-SC연합미람가명현강저조기유선암SLNB적가음성솔.
Objective To study the feasibility and accuracy of sentinel lymph node biopsy(SLNB)in early breast cancer.Methods In 76 cases of T1 or T2 breast cancer,sentinel lymph nodes identified by 99Tcm-sulfur colloid (99Tcm-SC )combining methylene blue were excised for biopsy. Sentinel lymph node was examined pathologically to observe the conformance rate and to study value of the combination approach of SLNB of early breast cancer.Results Sentinel lymph node was identified in 76 cases.In 7 cases axillary lymph node dissection was performed because the SLNB was positive.The sensitivity rate of 99Tcm-SC and methylene blue method was 85.7％(6/7)and 71.4％ (5/7 ).The accuracy rate of 99Tcm-SC and methylene blue method was 98.7 ％ (75/76)and 97.4％ (74/76).The false negative rate of 99Tcm-SC and methylene blue method was 14.3％ (1/7)and 28.6％(2/7).The sensitivity rate and the accuracy rate of combination method was 100％ (7/7,76/76).The false positive rate was zero(0/7).Conclusion 99Tcm-SC combining methylene blue can decrease the false negative rate of SLNB in early breast cancer.
