中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2009年
18期
12-14,27
,共4页
多系统萎缩%临床分析%早期诊断
多繫統萎縮%臨床分析%早期診斷
다계통위축%림상분석%조기진단
Multiple system atrophy%Clinical analysis%Early diagnosis
目的 探讨多系统萎缩(MSA)的临床表现,评价辅助检查对其I临床早期诊断的意义.方法 回顾性分析我院及长征医院2006年1月～2008年12月诊治的19例MSA患者的临床资料及主要辅助检查.结果 多系统萎缩是一组缓慢起病,逐渐加重的疾病,临床表现有自主神经功能障碍、小脑共济失调和帕金森综合征.植物神经症状出现较早,锥体外系症状是MSA最常见的运动异常,这两者是MSA容易误诊的主要原因.神经影像显示脑萎缩和葡萄糖代谢减低;肛门括约肌肌电图检查具有较高敏感度和特异度.结论 MSA临床表现复杂多样,早期易误诊.依据详细的病史和全面的神经系统检查,并辅以相关检查,可提高MSA早期诊断的准确性.
目的 探討多繫統萎縮(MSA)的臨床錶現,評價輔助檢查對其I臨床早期診斷的意義.方法 迴顧性分析我院及長徵醫院2006年1月～2008年12月診治的19例MSA患者的臨床資料及主要輔助檢查.結果 多繫統萎縮是一組緩慢起病,逐漸加重的疾病,臨床錶現有自主神經功能障礙、小腦共濟失調和帕金森綜閤徵.植物神經癥狀齣現較早,錐體外繫癥狀是MSA最常見的運動異常,這兩者是MSA容易誤診的主要原因.神經影像顯示腦萎縮和葡萄糖代謝減低;肛門括約肌肌電圖檢查具有較高敏感度和特異度.結論 MSA臨床錶現複雜多樣,早期易誤診.依據詳細的病史和全麵的神經繫統檢查,併輔以相關檢查,可提高MSA早期診斷的準確性.
목적 탐토다계통위축(MSA)적림상표현,평개보조검사대기I림상조기진단적의의.방법 회고성분석아원급장정의원2006년1월～2008년12월진치적19례MSA환자적림상자료급주요보조검사.결과 다계통위축시일조완만기병,축점가중적질병,림상표현유자주신경공능장애、소뇌공제실조화파금삼종합정.식물신경증상출현교조,추체외계증상시MSA최상견적운동이상,저량자시MSA용역오진적주요원인.신경영상현시뇌위축화포도당대사감저;항문괄약기기전도검사구유교고민감도화특이도.결론 MSA림상표현복잡다양,조기역오진.의거상세적병사화전면적신경계통검사,병보이상관검사,가제고MSA조기진단적준학성.
Objective To explore the clinical manifestations of multiple system atrophy(MSA), and assess the significance of the assistant examination for the early diagnosis. Methods The clinical and assistant examination data of 19 cases of MSA were retrospectively analyzed. Results Multiple system atrophy comprise a diverse group of diseases which slowly onset,and gradually increase. The clinical manifestations were autonomic nerve dysfunction,cerebellar ataxia and Parkinsonism.The autonomic nerve symptoms were the early clinical manifestation,and the extrapyramidal symptoms were the optima frequent motion abnormality.These were the two main reasons for MSA to be misdiagnosised. Brain atrophy brain atrophy and hypometabolism of glucose were detected in the Neuroimaging imaging. Anal sphincter(EAS) eletromyography(EMG) was sensitive and specific. Conclusion Clinical manifestations of this disease are complex and diverse early in the disease,we often misdiagnosed.Based on detailed medical history and comprehensive examination of the nervous system,and supplemented by relevant inspection,we can improve the accuracy of early diagnosis of MSA.
