中华泌尿外科杂志
中華泌尿外科雜誌
중화비뇨외과잡지
CHINESE JOURNAL OF UROLOGY
2012年
9期
696-698
,共3页
药物疗法,联合%行为疗法%膀胱过度活动症
藥物療法,聯閤%行為療法%膀胱過度活動癥
약물요법,연합%행위요법%방광과도활동증
Drug therapy,combination%Behavior therapy%Overactive bladder
目的 探讨药物联合行为干预治疗输尿管留置双J管后膀胱过度活动症(OAB)的疗效. 方法 输尿管留置双J管后OAB患者107例.男48例,女59例.年龄27～ 58岁,平均41岁.随机分为2组,A组(55例)为药物联合行为干预措施,行为措施包括患者健康教育、及时或延迟排尿、膀胱训练、盆底肌群锻炼；B组(52例)单用药物治疗,药物应用洒石酸托特罗定2 mg2次/d,阿呋唑嗪2.5 mg3次/d.连续应用1个月后随访,统计学比较2组治疗前后膀胱过度活动症评分( OABSS)及生活质量评分情况. 结果 A组患者治疗前后尿急评分分别为(3.5±0.9)与(0.9±0.2)分,OABSS评分分别为(10.7±2.0)与(3.9±1.8)分,生活质量评分(QOL)分别为(50.8 ±15.9)与(28.9±13.1)分,治疗前后评分差异均有统计学意义(P＜0.05).B组治疗前后尿急评分分别为(3.4±1.0)与(1.9±0.5)分,OABSS评分分别为(10.6±4.8)与(5.6±1.7)分,治疗前后差异均有统计学意义(P ＜0.05)；QOL评分分别为(50.7±16.1)与(39.9±14.2)分,治疗前后差异无统计学意义(P＞0.05).两组治疗后尿急评分、OABSS评分及QOL评分差异均有统计学意义(P＜0.05).结论 酒石酸托特罗定和阿呋唑嗪可以有效缓解输尿管留置双J管后OAB患者的尿急症状并降低OABSS评分,药物治疗联合行为干预措施疗效好于单用药物.
目的 探討藥物聯閤行為榦預治療輸尿管留置雙J管後膀胱過度活動癥(OAB)的療效. 方法 輸尿管留置雙J管後OAB患者107例.男48例,女59例.年齡27～ 58歲,平均41歲.隨機分為2組,A組(55例)為藥物聯閤行為榦預措施,行為措施包括患者健康教育、及時或延遲排尿、膀胱訓練、盆底肌群鍛煉；B組(52例)單用藥物治療,藥物應用灑石痠託特囉定2 mg2次/d,阿呋唑嗪2.5 mg3次/d.連續應用1箇月後隨訪,統計學比較2組治療前後膀胱過度活動癥評分( OABSS)及生活質量評分情況. 結果 A組患者治療前後尿急評分分彆為(3.5±0.9)與(0.9±0.2)分,OABSS評分分彆為(10.7±2.0)與(3.9±1.8)分,生活質量評分(QOL)分彆為(50.8 ±15.9)與(28.9±13.1)分,治療前後評分差異均有統計學意義(P＜0.05).B組治療前後尿急評分分彆為(3.4±1.0)與(1.9±0.5)分,OABSS評分分彆為(10.6±4.8)與(5.6±1.7)分,治療前後差異均有統計學意義(P ＜0.05)；QOL評分分彆為(50.7±16.1)與(39.9±14.2)分,治療前後差異無統計學意義(P＞0.05).兩組治療後尿急評分、OABSS評分及QOL評分差異均有統計學意義(P＜0.05).結論 酒石痠託特囉定和阿呋唑嗪可以有效緩解輸尿管留置雙J管後OAB患者的尿急癥狀併降低OABSS評分,藥物治療聯閤行為榦預措施療效好于單用藥物.
목적 탐토약물연합행위간예치료수뇨관류치쌍J관후방광과도활동증(OAB)적료효. 방법 수뇨관류치쌍J관후OAB환자107례.남48례,녀59례.년령27～ 58세,평균41세.수궤분위2조,A조(55례)위약물연합행위간예조시,행위조시포괄환자건강교육、급시혹연지배뇨、방광훈련、분저기군단련；B조(52례)단용약물치료,약물응용쇄석산탁특라정2 mg2차/d,아부서진2.5 mg3차/d.련속응용1개월후수방,통계학비교2조치료전후방광과도활동증평분( OABSS)급생활질량평분정황. 결과 A조환자치료전후뇨급평분분별위(3.5±0.9)여(0.9±0.2)분,OABSS평분분별위(10.7±2.0)여(3.9±1.8)분,생활질량평분(QOL)분별위(50.8 ±15.9)여(28.9±13.1)분,치료전후평분차이균유통계학의의(P＜0.05).B조치료전후뇨급평분분별위(3.4±1.0)여(1.9±0.5)분,OABSS평분분별위(10.6±4.8)여(5.6±1.7)분,치료전후차이균유통계학의의(P ＜0.05)；QOL평분분별위(50.7±16.1)여(39.9±14.2)분,치료전후차이무통계학의의(P＞0.05).량조치료후뇨급평분、OABSS평분급QOL평분차이균유통계학의의(P＜0.05).결론 주석산탁특라정화아부서진가이유효완해수뇨관류치쌍J관후OAB환자적뇨급증상병강저OABSS평분,약물치료연합행위간예조시료효호우단용약물.
Objective To explore the efficacy of combination medical therapy with behavior intervention on overactive bladder secondary to indwelling double J ureteral stent.Methods One hundred and seven OAB patients secondary to indwelling double J ureteral stent,with 48 males,59 females,age 27-58 (41 years old on average) were randomly divided into two groups.Group A were treated with the combination of medical therapy and behavior intervention.Group B were treated with only medical therapy.The regimen of medical therapy is tolterodine 2 mg,twice daily and alfuzosin 2.5 mg,three times daily.The patients were followed-up 1 month later and OABSS score was obtained.Results The OABSS urgency score was (3.5 ±0.9) and (0.9 ±0.2),the OABSS total score was (10.7 ±2.0) and (3.9 ±1.8),and QOL was (50.8 ± 15.9 ) and (28.9 ± 13.1 ) before and after the therapy in group A ( P ＜ 0.05 ),which showed great improvement after treatment.In group B,the urgency score was (3.4 ± 1.0) and ( 1.9 ± 0.5 ) and OABSS score was ( 10.6 ± 4.8 ) and (5.6 ± 1.7) before and after treatment,whose improvement is statistically significant ( P ＜ 0.05 ).The QOL score was ( 50.7 ± 16.1 ) and ( 39.9 ± 14.2 ) before and after treatment,whose improvement is not statistically significant (P ＞0.05).After the treatment,the difference of the improvement in urgency,total and the QOL scores between groups A and group B is statistically significant (P ＜ 0.05 ).Conclusions Tolterodine and alfuzosin can effectively alleviate overactive bladder symptoms secondary to indwelling double J ureteral stent by combining medical therapy with behavior intervention.
