CAJ | 학술논문

目的分析阴茎癌患者临床病理特征以及对患者术后生存情况的影响. 方法回顾性分析2002 - 2010年就诊的93例阴茎癌患者资料.计算阴茎癌的临床病理特征分布,以及不同病理类型阴茎癌的术后生存情况.采用Kaplan-Meier法绘制生存曲线,计算生存率,并采用log-rank 检验进行生存比较. 结果 93例患者年龄23 ～ 82岁,中位年龄为51岁.病理类型以鳞状细胞癌最常见,为87例(93.5％).61例获随访,随访2～89个月,平均28个月.3例疣状癌分别随访12、19、67个月,均无复发生存.55例侵袭性阴茎鳞状细胞癌患者中11例死于阴茎癌肿瘤转移,术后生存时间为2～24个月,平均10个月,2年生存率为75.7％(95％CI为63.O％～88.4％).12例淋巴结转移者6例死亡,43例淋巴结阴性患者5例死亡,两者比较差异有统计学意义(P=0.000). 结论阴茎癌以鳞状细胞癌最为常见,伴有淋巴结转移患者的预后明显较差.疣状癌发病率较低,很少出现淋巴结转移,预后良好.
목적 분석음경암환자림상병리특정이급대환자술후생존정황적영향. 방법 회고성분석2002 - 2010년취진적93례음경암환자자료.계산음경암적림상병리특정분포,이급불동병리류형음경암적술후생존정황.채용Kaplan-Meier법회제생존곡선,계산생존솔,병채용log-rank 검험진행생존비교. 결과 93례환자년령23 ～ 82세,중위년령위51세.병리류형이린상세포암최상견,위87례(93.5％).61례획수방,수방2～89개월,평균28개월.3례우상암분별수방12、19、67개월,균무복발생존.55례침습성음경린상세포암환자중11례사우음경암종류전이,술후생존시간위2～24개월,평균10개월,2년생존솔위75.7％(95％CI위63.O％～88.4％).12례림파결전이자6례사망,43례림파결음성환자5례사망,량자비교차이유통계학의의(P=0.000). 결론 음경암이린상세포암최위상견,반유림파결전이환자적예후명현교차.우상암발병솔교저,흔소출현림파결전이,예후량호.
Objective To analyze the clinicopathological characteristics and survival time of penile cancer after surgery. Methods The clinicopathological data of 93 cases of penile cancers patients treated from January 2002 to December 2010 were collected retrospectively.The Kaplan-Meier method was used to draw the survival function and calculate the survival rate.Log-rank test was further used to compare survival difference. Results The median age of the 93 patients was 51 years ( range,23 to 82).Squamous carcinoma was most common with 87 eases (93.5％) in our group.Sixty-one patients were successfully followed up and the median follow up duration was 28 months(range,2 to 89 months).All 3 cases of verrucous carcinoma had progression free survive after surgery after follow up of 12,19,and 67 months.In the 55 patients with penile invasive squamous carcinoma,11 patients died of metastatic disease with a median survival time of 10 months ( range,2 to 24 months).Two years cumulative survival rate was 75.7％ (95％ CI 63.0％ to 88.4％ ).Six cases of 12 patients with lymph node metastasis died of penile cancer while only 5 cases of 43 patients without lymphnode metastasis died.The survival difference was significant (log rank,P =0.000). Conclusions Squamous carcinoma is the most common type,and patients with lymphnode metastasis have poor prognosis.Verrucous carcinoma has good prognosis.