CAJ | 학술논문

目的探讨门冬氨酸鸟氨酸(瑞甘)对阻塞性黄疸患者围手术期肝功能的影响.方法因阻塞性黄疸而手术的58例患者随机选择分为瑞甘组(治疗组)32例和常规护肝组(对照组)26例,检测入院时、术前及术后肝功能及内毒素.结果应用瑞甘治疗在围手术期可明显保护肝功能,与对照组比较差异有统计学意义(P<0.05),且波动幅度较小.瑞甘治疗后在术前、术后均能降低血浆内毒素的浓度(P<0.05),改善阻黄时的内毒素血症.结论瑞甘在阻塞性黄疸围手术期能改善肝功能和内毒素血症.
목적 탐토문동안산조안산(서감)대조새성황달환자위수술기간공능적영향.방법 인조새성황달이수술적58례환자수궤선택분위서감조(치료조)32례화상규호간조(대조조)26례,검측입원시、술전급술후간공능급내독소.결과 응용서감치료재위수술기가명현보호간공능,여대조조비교차이유통계학의의(P<0.05),차파동폭도교소.서감치료후재술전、술후균능강저혈장내독소적농도(P<0.05),개선조황시적내독소혈증.결론 서감재조새성황달위수술기능개선간공능화내독소혈증.
Objective To investigate the effect of Ruigan (L-omithine-L-aspartate) on liver function of perio-perative treatment. Methods 58 patients with obstructive jaundice and having been done operation were randomly di-vided into two groups:ruigan group (cured group,32 cases) and routine hugan group (control group,26 cases). The levels of liver function and endotoxin were detected when being in hospital, before operation and after operation re-spectively. Results Treatment with ruigan could improve the liver function in perioperation, which has significant difference when compared to the control group (P < 0.05).. Ruigan could reduce the level of endotoxin before and af-ter operation (P < 0.05) and improve endotoxaemia in obstructive jaundice. Conclusion Ruigan would improve the liver function and the endotoxaemia in the perioperative obstructive jaundice.