CAJ | 학술논문

目的根据乳腺导管内癌的临床及病理特点探索其个体化治疗方式及其预后观察.方法根据每例乳腺导管内癌的临床及病理特点采用个体化综合治疗方式,观察其预后.结果本组67例患者根据肿块大小,术中冰冻病理切缘情况,来确定手术方式.其中象限切除术18例,肿块切除活检术10例,乳房单纯切除术16例或加Ⅰ期乳房假体植入术14例,乳腺肿块切除术+乳腺癌改良根治术4例,保乳术5例.术后辅助化疗33例,放疗23例,内分泌治疗42例.5年随访,2例死亡.不同术式组五年复发率和生存率无统计学差别.结论导管内癌的治疗主要根据肿瘤大小来决定不同手术方式,同时结合肿瘤组织学特点、性激素受体等因素综合设计个体化治疗.
목적 근거유선도관내암적림상급병리특점탐색기개체화치료방식급기예후관찰.방법 근거매례유선도관내암적림상급병리특점채용개체화종합치료방식,관찰기예후.결과 본조67례환자근거종괴대소,술중빙동병리절연정황,래학정수술방식.기중상한절제술18례,종괴절제활검술10례,유방단순절제술16례혹가Ⅰ기유방가체식입술14례,유선종괴절제술+유선암개량근치술4례,보유술5례.술후보조화료33례,방료23례,내분비치료42례.5년수방,2례사망.불동술식조오년복발솔화생존솔무통계학차별.결론 도관내암적치료주요근거종류대소래결정불동수술방식,동시결합종류조직학특점、성격소수체등인소종합설계개체화치료.
Objective To explore ductal carcinoma in stit individual treatment,according to clinical and pathological features of breast ductal carcinoma in situ.Methods Analysis of 67 cases of ductal carcinoma in situ in patients with clinical data.Results According to tumor size,intraoperative frozen pathology to determine the surgical method with 67 patients.Breast quadrant resection 18 cases,Breast tumor resection 10 cases,Breast tumor resection and Modified radical mastectomy 4 cases,Breast conserving surgery 5 cases.Postoperative adjuvant chemotherapy 33 cases,radiotherapy 23 cases,endocrine therapy 42 cases.Adjuvant treatment of patients with Chinese medicine.5-year follow-up,2 cases died of breast cancer recurrence,other patients were alive.5-year recurrence rate and 5-year survival rate were not statistically significant between different groups.Conclusion The treatment of ductal carcinoma in situ mainly based on tumor size,to determine the surgical method,combined with histological features hormone receptors to design individual treatment programs.