CAJ | 학술논문

目的：测定药物中的抗坏血酸含量。方法：利用抗坏血酸对铁(Ⅲ)-4-(2-苯并噻唑偶氮)邻苯二酚-乳化剂OP络合物的还原作用，生成铁(Ⅱ)-4-(2-苯并噻唑偶氮)邻苯二酚-乳化剂OP络合物，使用分光光度法间接测定抗坏血酸。结果：测定了抗坏血酸片和Vc注射液的含量，并与碘量法比较，同时还测定了标准回收率。结论：此法方便快捷，测定含量与碘量法一致，结果可靠。
목적：측정약물중적항배혈산함량。방법：이용항배혈산대철(Ⅲ)-4-(2-분병새서우담)린분이분-유화제OP락합물적환원작용，생성철(Ⅱ)-4-(2-분병새서우담)린분이분-유화제OP락합물，사용분광광도법간접측정항배혈산。결과：측정료항배혈산편화Vc주사액적함량，병여전량법비교，동시환측정료표준회수솔。결론：차법방편쾌첩，측정함량여전량법일치，결과가고。
Objective:To analyse the content of ascorbic acid in medicine.Methods:Ascorbic acid was determined by spectrophotometric method based on the formation of iron(Ⅱ)-4-(2-benzothiazolylazo) pyrocatechol-OP complex which was the product of the redox reaction between ascorbic acid and iron (Ⅲ)-4-(2-benzothiazolylazo) pyrocatechol-OP complex. The proposed method is rapid and satisfactory.Results:The content of Ascorbic Acid in medicines have been determined and compared with the results of iodine method.Conclution:The proposed method is rapid and satisfaction and the results is consistence with the iodine method.