北京医学
北京醫學
북경의학
BEIJING MEDICAL JOURNAL
2001年
1期
22-24
,共3页
螺杆菌,幽门%十二指肠溃疡
螺桿菌,幽門%十二指腸潰瘍
라간균,유문%십이지장궤양
目的 研究奥美拉唑(奥克)和泰胃美三联疗法治疗幽门螺杆菌(HP)相关性十二指肠溃疡的愈合率、HP根除率、主要症状缓解率及其安全性。方法 经胃镜证实的十二指肠溃疡患者采用随机抽样、配对分组法分为奥克三联组(A组)和泰胃美三联组(B组)；2周为一疗程，停药4周后复查胃镜。结果 溃疡愈合率A组为90.9%，B组为42.1%，有极显著性差异P＜0.001。HP根除率A组为86.4%，B组为78.9%，P＞0.05，无显著性差异。1周疼痛、烧心和反酸缓解率A、B两组均有显著性差异。结论 奥克2周三联疗法对十二指肠溃疡的疗效及症状缓解率明显优于泰胃美，而根除HP无明显差异。
目的 研究奧美拉唑(奧剋)和泰胃美三聯療法治療幽門螺桿菌(HP)相關性十二指腸潰瘍的愈閤率、HP根除率、主要癥狀緩解率及其安全性。方法 經胃鏡證實的十二指腸潰瘍患者採用隨機抽樣、配對分組法分為奧剋三聯組(A組)和泰胃美三聯組(B組)；2週為一療程，停藥4週後複查胃鏡。結果 潰瘍愈閤率A組為90.9%，B組為42.1%，有極顯著性差異P＜0.001。HP根除率A組為86.4%，B組為78.9%，P＞0.05，無顯著性差異。1週疼痛、燒心和反痠緩解率A、B兩組均有顯著性差異。結論 奧剋2週三聯療法對十二指腸潰瘍的療效及癥狀緩解率明顯優于泰胃美，而根除HP無明顯差異。
목적 연구오미랍서(오극)화태위미삼련요법치료유문라간균(HP)상관성십이지장궤양적유합솔、HP근제솔、주요증상완해솔급기안전성。방법 경위경증실적십이지장궤양환자채용수궤추양、배대분조법분위오극삼련조(A조)화태위미삼련조(B조)；2주위일료정，정약4주후복사위경。결과 궤양유합솔A조위90.9%，B조위42.1%，유겁현저성차이P＜0.001。HP근제솔A조위86.4%，B조위78.9%，P＞0.05，무현저성차이。1주동통、소심화반산완해솔A、B량조균유현저성차이。결론 오극2주삼련요법대십이지장궤양적료효급증상완해솔명현우우태위미，이근제HP무명현차이。
Objective To study the effect of omeperazole triple therapy and tagamet triple therapy on the treatment of helicobacter pylori (HP) related duodenal ulcer (DU),and to compare the healing rate,HP eradicate rate,major symptoms relieve rate and safety between the two regimens.Methods All diagnoses of DU were confirmed by gastroendoscopy.The patients were divided into omeprazole triple therapy group (group A) and tagamet triple therapy group (group B) by a double-bland randomized way.The therapy period was 2 weeks.Four weeks later,gastroendoscopy was reexamed.Results DU healing rate in group A was 90.9%,and in group B was 42.1%( P＜0.001).HP eradicate rate in group A was 86.4% and in group B was 78.9% (P＞0.05).One week pain,burning heart and acid reflux relieve rate was significantly higher in group A than in group B.Conclusions The effect of 2 weeks omeprazole triple therapy is much better than tagamet triple therapy in DU.But HP eradicate rate is samilar in the two groups.
