CAJ | 학술논문

目的：观察自制中药制剂化症注射液治疗病态窦房结综合征的疗效，探索化症液应用新指征．方法：对36例病窦综合征患者用化症液治疗，进行前瞻性研究，采用心电图、动态心电图、食管电生理检查评价窦房结功能，结合临床症状进行疗效评判，并随访0.5～3.5年．结果：化症液治疗1～4个疗程后全部病例均有明显疗效，临床症状、心电图、动态心电图及窦房结功能均有不同程度改善．晕厥症状消失，治疗后平均提高心率达12次/min；治疗后24 h总心率明显提高，窦房结恢复时间(SNRT)、校正窦房结恢复时间(SNRTc)及窦房传导时间(SACT)均有改善．结论：化症注射液对病窦综合征有较好的辅助对症治疗作用，配合西医病因治疗，可明显提高心率，降低晕厥发生，改善窦房结功能，值得临床推广应用．
목적：관찰자제중약제제화증주사액치료병태두방결종합정적료효，탐색화증액응용신지정．방법：대36례병두종합정환자용화증액치료，진행전첨성연구，채용심전도、동태심전도、식관전생리검사평개두방결공능，결합림상증상진행료효평판，병수방0.5～3.5년．결과：화증액치료1～4개료정후전부병례균유명현료효，림상증상、심전도、동태심전도급두방결공능균유불동정도개선．훈궐증상소실，치료후평균제고심솔체12차/min；치료후24 h총심솔명현제고，두방결회복시간(SNRT)、교정두방결회복시간(SNRTc)급두방전도시간(SACT)균유개선．결론：화증주사액대병두종합정유교호적보조대증치료작용，배합서의병인치료，가명현제고심솔，강저훈궐발생，개선두방결공능，치득림상추엄응용．
Objective to study the therapeutic efficacy of Huazheng injection in SSS and explore new indications of it Huazheng was a traditional Chinese medicine produced by our hospital. Methods We prospectively studied 36 cases of SSS treated by Huazheng injection and followed up 0.5～3.5 years. Sinus node function was evaluated by ECG、24-hour Holter monitoring and transesophageal electrophysiologic examination. Results All cases had significant effects after 1～4 courses of treatment. Syncope disappeared. Average HR increased 12 beats/min, total HR of 24hs also increased obviously. SNRT、SNRTc and SACT all improved. Conclusion Huazheng injection could increase HR、improve sinus node function and decrease syncope attack, so it was a better supplementary drug for SSS.