药学学报
藥學學報
약학학보
ACTA PHARMACEUTICA SINICA
2003年
1期
32-36
,共5页
孙兰%朱久香%余竞光%余冬蕾%李德宇%周立东
孫蘭%硃久香%餘競光%餘鼕蕾%李德宇%週立東
손란%주구향%여경광%여동뢰%리덕우%주립동
圆滑番荔枝%番荔枝科%番荔素%glabrencin A%glabrencin B
圓滑番荔枝%番荔枝科%番荔素%glabrencin A%glabrencin B
원활번려지%번려지과%번려소%glabrencin A%glabrencin B
目的研究圆滑番荔枝(Annona glabra)种子的抗肿瘤活性成分.方法利用色谱技术分离纯化, 根据化合物的理化性质和光谱数据鉴定结构.结果从己烷提取物鉴定18个化合物,其中14个为番荔素:glabrencin A (1), bullatencin (2), glabrencin B (3), uvariamicin-I (4), uvariamicin-II (5), uvariamicin-III (6), reticulatain-1 (7), desacetyluvaricin (8), 4-deoxyasimicin (9), asimicin (10), bullatacin (11), squamocin (12), motrilin (13), cherimolin-2 (14);豆甾醇(stigmasterol,15)及脂肪酸酰胺混合物:棕榈酸酰胺(palmitic amide,16),硬脂酸酰胺(stearic amide,17)和花生酸酰胺(arachidic amide,18).结论 glabrencin A (1),glabrencin B (3)为新番荔素;2,4～7,9,11,13,16～18是首次从该植物中分离得到.
目的研究圓滑番荔枝(Annona glabra)種子的抗腫瘤活性成分.方法利用色譜技術分離純化, 根據化閤物的理化性質和光譜數據鑒定結構.結果從己烷提取物鑒定18箇化閤物,其中14箇為番荔素:glabrencin A (1), bullatencin (2), glabrencin B (3), uvariamicin-I (4), uvariamicin-II (5), uvariamicin-III (6), reticulatain-1 (7), desacetyluvaricin (8), 4-deoxyasimicin (9), asimicin (10), bullatacin (11), squamocin (12), motrilin (13), cherimolin-2 (14);豆甾醇(stigmasterol,15)及脂肪痠酰胺混閤物:棕櫚痠酰胺(palmitic amide,16),硬脂痠酰胺(stearic amide,17)和花生痠酰胺(arachidic amide,18).結論 glabrencin A (1),glabrencin B (3)為新番荔素;2,4～7,9,11,13,16～18是首次從該植物中分離得到.
목적연구원활번려지(Annona glabra)충자적항종류활성성분.방법이용색보기술분리순화, 근거화합물적이화성질화광보수거감정결구.결과종기완제취물감정18개화합물,기중14개위번려소:glabrencin A (1), bullatencin (2), glabrencin B (3), uvariamicin-I (4), uvariamicin-II (5), uvariamicin-III (6), reticulatain-1 (7), desacetyluvaricin (8), 4-deoxyasimicin (9), asimicin (10), bullatacin (11), squamocin (12), motrilin (13), cherimolin-2 (14);두치순(stigmasterol,15)급지방산선알혼합물:종려산선알(palmitic amide,16),경지산선알(stearic amide,17)화화생산선알(arachidic amide,18).결론 glabrencin A (1),glabrencin B (3)위신번려소;2,4～7,9,11,13,16～18시수차종해식물중분리득도.
