CAJ | 학술논문

本文合成了新型三联吡啶铜配合物[Cu(ttpy)(acetone)Cl]·(NO3)(H2O)3(ttpy=4'-p-tolyl-2,2':6,2"-terpyridine),通过元素分析和X-射线单晶衍射进行结构表征.该配合物属三斜晶系,空间群为P1-,晶胞参数为a=0.8476(3)nm,b=1.2650(5)nm,c=1.4227(5)nm,α=111.017(7)°,β=92.174(7)°,γ=90.562(7)°,V=1.4225(9)nm3,Z=2,Dc=1.309 Mg·m-3,μ(Mo Kα)=9.00 cm-1,F(000)=578,R1=0.0633,wR=0.1414.在配合物中,中心铜原子的配位环境为变形四方锥,并通过分子内和分子间的C-H…Cl和C-H…O氢键作用形成三维梯状结构.凝胶电泳结果表明,在pH=7.4,温度37°,以抗坏血酸为还原剂的条件下,该配合物对超螺旋pUC19 DNA表现出一定的切割活性.紫外-可见光谱结果显示,该配合物与四种核苷的反应活性顺序为:5'-GMP>5'-AMP>5'.TMP≈5'-CMP.
본문합성료신형삼련필정동배합물[Cu(ttpy)(acetone)Cl]·(NO3)(H2O)3(ttpy=4'-p-tolyl-2,2':6,2"-terpyridine),통과원소분석화X-사선단정연사진행결구표정.해배합물속삼사정계,공간군위P1-,정포삼수위a=0.8476(3)nm,b=1.2650(5)nm,c=1.4227(5)nm,α=111.017(7)°,β=92.174(7)°,γ=90.562(7)°,V=1.4225(9)nm3,Z=2,Dc=1.309 Mg·m-3,μ(Mo Kα)=9.00 cm-1,F(000)=578,R1=0.0633,wR=0.1414.재배합물중,중심동원자적배위배경위변형사방추,병통과분자내화분자간적C-H…Cl화C-H…O경건작용형성삼유제상결구.응효전영결과표명,재pH=7.4,온도37°,이항배혈산위환원제적조건하,해배합물대초라선pUC19 DNA표현출일정적절할활성.자외-가견광보결과현시,해배합물여사충핵감적반응활성순서위:5'-GMP>5'-AMP>5'.TMP≈5'-CMP.
A novel copper(Ⅱ)terpyridine complex[Cu(ttpy)(acetone)Cl]·(NO3)(H2O)3(ttpy=4'-p-tolyl-2,2':6,2"-terpyridine) had been synthesized and structurally characterized.The complex crystallized in the triclinic system,.space group P1- with cell parameters:a=0.8476(3)nm,b=1.2650(5)nm,c=1.4227(5),α=111.017(7)°,β=92.174(7)°, wR2=0.1414.The copper center was situated in a distorted square pyramidal(4+1)CuN3X2 coordination geometry with terpyriMine acting as an equatorial tridentate ligand.The 3D ladder-like structure was connected by intra-and concentration in the presence of ascorbic acid.The reactivity of the complex towards four mononucleotides with the order:5'-GMP>5'-AMP>5'.TMP≈5'-CMP,was determined by UV-Vis spectroscopy.CCDC:625295.