CAJ | 학술논문

目的分析196例药物性肝炎患者的临床资料,为临床安全用药提供帮助.方法回顾性分析196例药物性肝炎患者的临床表现、致病药物种类、药物引起肝损害的出现时间以及各型药物性肝炎的ALT水平特点.结果引起药物性肝炎的药物种类众多,其中中药占了很高比例(91/196,46.43%).本组药物性肝炎中肝细胞型59例、胆汁淤积型69例和混合型68例.结论了解药物性肝炎的特点,有助于提高临床医师对药物性肝炎的认识,提高临床用药的安全性.
목적 분석196례약물성간염환자적림상자료,위림상안전용약제공방조.방법 회고성분석196례약물성간염환자적림상표현、치병약물충류、약물인기간손해적출현시간이급각형약물성간염적ALT수평특점.결과 인기약물성간염적약물충류음다,기중중약점료흔고비례(91/196,46.43%).본조약물성간염중간세포형59례、담즙어적형69례화혼합형68례.결론 료해약물성간염적특점,유조우제고림상의사대약물성간염적인식,제고림상용약적안전성.
Objective To analyse, the clinical data of 196 cases of drng-induced hepatitis and to improve the medication safety in clinical practice. Methods Retrospective analysis on the clinical manifestations, species of drugs inducing liver injury,time interval of drug application and liver injury,features of ALT level in 196 cases of drng-induced hepatitis. Results Species of drugs inducing hepatitis were diverse, and among the total, Chinese herbal drugs were very common(91/196,46.43% ).There were 59 cases of hepatocyte-injury type, 69 cases of cholestasis type and 68 cases of mixed type in this drug-induced hepatitis group. Conclusions Understanding the features of drug-induced hepatitis is helpful to improve the medication safety in clinical practice.