CAJ | 학술논문

目的探讨老年胃食管反流病(GERD)患者的临床特征,为临床诊断、治疗提供帮助.方法根据GERD蒙特利尔的标准、中国胃食管反流病共识意见等,将GERD患者分为老年组(年龄≥65岁)与中青年组(年龄＜65岁);通过问卷调查,分析2组GERD患者的食管裂孔疝(HH)、食管炎(洛杉矶标准)、临床症状(反流、烧心等)、生活质量.结果两组性别比差异无统计学意义(P＞0.05).与中青年GERD患者比较:老年患者重度食管炎(LC级+LD级)比例高(P＜0.05);典型反酸、烧心症状轻(P＜0.05),食管外症状发生率高(P＜0.05);但HH发生率差异无统计学意义(P＞0.05).老年患者生理功能、总体健康、活力、社会功能、精神健康、躯体生理健康总评和精神心理健康总评积分与年轻组差异无统计学意义(P＞0.05),仅生理职能、躯体疼痛、情感职能积分较中青年组高(P＜0.05).结论老年GERD患者典型反流症状(反食、烧心)较少见,易发生重度食管炎,但老年GERD患者生活质量无明显下降.
목적 탐토노년위식관반류병(GERD)환자적림상특정,위림상진단、치료제공방조.방법 근거GERD몽특리이적표준、중국위식관반류병공식의견등,장GERD환자분위노년조(년령≥65세)여중청년조(년령＜65세);통과문권조사,분석2조GERD환자적식관렬공산(HH)、식관염(락삼기표준)、림상증상(반류、소심등)、생활질량.결과 량조성별비차이무통계학의의(P＞0.05).여중청년GERD환자비교:노년환자중도식관염(LC급+LD급)비례고(P＜0.05);전형반산、소심증상경(P＜0.05),식관외증상발생솔고(P＜0.05);단HH발생솔차이무통계학의의(P＞0.05).노년환자생리공능、총체건강、활력、사회공능、정신건강、구체생리건강총평화정신심리건강총평적분여년경조차이무통계학의의(P＞0.05),부생리직능、구체동통、정감직능적분교중청년조고(P＜0.05).결론 노년GERD환자전형반류증상(반식、소심)교소견,역발생중도식관염,단노년GERD환자생활질량무명현하강.
Objective To analyze clinical characteristics of gastroesophageal reflux disease(GERD) in aged patients for improvement of diagnosis and treatemcnt. Methods The reflux disease questionnaire was performed in patients diagnosed as GERD based on Montreal definition and classification as well as Rome Ⅲ criteria.All patients were divided into elderly group (≥65 years) and control group(＜65 years). The incidence of hita[ hernia (HH), the frequencies of esophagitis (based on Los Angeles classification), clinical features, and quality of life were compared between two groups. Results There was no difference between two groups in male/female ratio and morbidity of HH(P＞0.05). In comparison with control group, the frequency of esophagitis graded as LC or LD increased and extra-esophageal symptoms were higher in elderly group (P＜ 0.05), but the lower typical symptoms (heartburn and regurgitation) were seen in the elderly group(P＜0.05). The scores of role physical, bodily pain and role emotional were higher in elderly group than those in control group (P＜0.05). There was no significant differences between two groups in physical function, vitality,social functioning, mental health, and general health. Conclusion The elderly GERD patients often have lower score of typical reflux symptoms (heartburn and regurgitation) and high incidence of severer esophagitis, but their quality of life is not significantly influenced.