中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2009年
3期
427-428
,共2页
林冰%严红莲%钟艳萍%李勉勤
林冰%嚴紅蓮%鐘豔萍%李勉勤
림빙%엄홍련%종염평%리면근
糖尿病,妊娠%C-反应蛋白质%体重指数
糖尿病,妊娠%C-反應蛋白質%體重指數
당뇨병,임신%C-반응단백질%체중지수
Diabetes,gestational%C-reactive pmteln%Glucose tolerance test
目的 探讨血清C-反应蛋白(CRP)水平在妊娠期糖尿病(GDM)发病中的作用.方法 选取经75g葡萄糖耐量试验(OGTY)确诊为GDM患者(GDM组)96例和糖耐量异常(IGT)妊娠妇女64例,并随机选择同期相匹配的糖耐量正常妊娠妇女160例(对照组),同时检测血清CRP水平.结果 GDM组CRP水平明显高于IGT和对照组(P＜0.05);CRP水平与孕前体重指数(BMI)、空腹血糖、空腹胰岛素呈正相关,相关系数分别为0.338、0.163和0.283,P值分别为0.0001、0.0169和0.0003.结论 CRP与GDM密切相关,参与了其发病机制.
目的 探討血清C-反應蛋白(CRP)水平在妊娠期糖尿病(GDM)髮病中的作用.方法 選取經75g葡萄糖耐量試驗(OGTY)確診為GDM患者(GDM組)96例和糖耐量異常(IGT)妊娠婦女64例,併隨機選擇同期相匹配的糖耐量正常妊娠婦女160例(對照組),同時檢測血清CRP水平.結果 GDM組CRP水平明顯高于IGT和對照組(P＜0.05);CRP水平與孕前體重指數(BMI)、空腹血糖、空腹胰島素呈正相關,相關繫數分彆為0.338、0.163和0.283,P值分彆為0.0001、0.0169和0.0003.結論 CRP與GDM密切相關,參與瞭其髮病機製.
목적 탐토혈청C-반응단백(CRP)수평재임신기당뇨병(GDM)발병중적작용.방법 선취경75g포도당내량시험(OGTY)학진위GDM환자(GDM조)96례화당내량이상(IGT)임신부녀64례,병수궤선택동기상필배적당내량정상임신부녀160례(대조조),동시검측혈청CRP수평.결과 GDM조CRP수평명현고우IGT화대조조(P＜0.05);CRP수평여잉전체중지수(BMI)、공복혈당、공복이도소정정상관,상관계수분별위0.338、0.163화0.283,P치분별위0.0001、0.0169화0.0003.결론 CRP여GDM밀절상관,삼여료기발병궤제.
Objective To discuss the effect of C-reactive protein(CRP)levels in pregnant women with gestational diabetes meatus(GDM).Methods To select 96 GDM women with 75 grams oral slum tolerance test(OGTF)and 64 pregnant women with impaired gluccose tolerance(IGT)respectively,and choose 160 normal pmgnant women with normal slucose tolerance(NGT)randomly as control group,then observe their serum CRP level at the same time.Results The serum CRP level in GDM group was significantly higher than IGT group and control group (P＜0.05).The sermn CRP level is positively related with pre-pregnancy body mass irdex(BMI),fasting bloodslope and fasting insulin,and the correlation coefficients are 0.338,0.163 and 0.283 respectively,and P values are 0.00001,0.0169 and 0.0003 respectively.Conclusion The blood sertlm C-reactive protein is closely related to GDM and involved in the pathogenesis of GDM.
