时珍国医国药
時珍國醫國藥
시진국의국약
LISHIZHEN MEDICINE AND MATERIA MEDICA RESEARCH
2008年
3期
641-643
,共3页
八角油%β-环糊精%包合物制备%均匀设计
八角油%β-環糊精%包閤物製備%均勻設計
팔각유%β-배호정%포합물제비%균균설계
Star anise oil%β-Cyclodextrin%Inclusion process%Uniform design
目的 研究β-环糊精对八角油的包合作用.方法 以挥发油包合率为指标,应用3因素6水平的均匀设计法,筛选出八角油包合物的最佳制备条件,即温度、研磨时间、样品与β-CD的比例.结果 实验得出最佳条件:当温度为35.0℃,研磨时间为4.0 h,八角茴香油与β-CD的比例1:13.0(ml:g)时,包合率为81.4%;红外测定包合作用是否完全.结论 优选得到的工艺结果稳定可行.
目的 研究β-環糊精對八角油的包閤作用.方法 以揮髮油包閤率為指標,應用3因素6水平的均勻設計法,篩選齣八角油包閤物的最佳製備條件,即溫度、研磨時間、樣品與β-CD的比例.結果 實驗得齣最佳條件:噹溫度為35.0℃,研磨時間為4.0 h,八角茴香油與β-CD的比例1:13.0(ml:g)時,包閤率為81.4%;紅外測定包閤作用是否完全.結論 優選得到的工藝結果穩定可行.
목적 연구β-배호정대팔각유적포합작용.방법 이휘발유포합솔위지표,응용3인소6수평적균균설계법,사선출팔각유포합물적최가제비조건,즉온도、연마시간、양품여β-CD적비례.결과 실험득출최가조건:당온도위35.0℃,연마시간위4.0 h,팔각회향유여β-CD적비례1:13.0(ml:g)시,포합솔위81.4%;홍외측정포합작용시부완전.결론 우선득도적공예결과은정가행.
Objective To study the inclusion complex of Star anise oil with β-cyclodextrin.Methods 3 factors and 6 levels of conditions for the preparation of the inclusion complex were selected by the uniform design.The ratio of Star anise oil in the inclusion complex WaS used as criterion in these experiments.The inclusion complex was made by pestling method.Results The best conditions of the inclusion complex were that:the ratio of Star anise oil and β-Cyclodextrin was l:13.0(mL/g),and grinding for 4.0 hours at 35.°C.The ratio of volatile oil in the inclusion complex WaS about 81.4％.And the inclusion complex Was identified by IR.Conclusion The optimized process is stable and highly efficient.
