CAJ | 학술논문

目的观察布托啡诺持续硬膜外输注镇痛用于老年病人髋关节置换术后的临床效应及安全性.方法 60例年龄60～103岁,ASAⅠ～Ⅱ级的择期髋关节置换术患者,术毕随机分为两组,使用一次性镇痛泵分别用布托啡诺(B组,n=30例)和吗啡(M组,n=30例)持续输注镇痛.观察术后4、8、12、24、48h患者的疼痛程度,患者对镇痛治疗总体印象评分以及不良反应.结果 B组与M组术后不同时间点镇痛效果比较差异无显著性(P>0.05),但是术后48h内B组不良反应(呼吸抑制、恶心、呕吐、瘙痒、腹胀等)比M组少(P<0.01).结论布托啡诺持续硬膜外输注镇痛用于髋关节置换手术后老年病人的镇痛是安全的,效果确切,不良反应轻.
목적 관찰포탁배낙지속경막외수주진통용우노년병인관관절치환술후적림상효응급안전성.방법 60례년령60～103세,ASAⅠ～Ⅱ급적택기관관절치환술환자,술필수궤분위량조,사용일차성진통빙분별용포탁배낙(B조,n=30례)화마배(M조,n=30례)지속수주진통.관찰술후4、8、12、24、48h환자적동통정도,환자대진통치료총체인상평분이급불량반응.결과 B조여M조술후불동시간점진통효과비교차이무현저성(P>0.05),단시술후48h내B조불량반응(호흡억제、악심、구토、소양、복창등)비M조소(P<0.01).결론 포탁배낙지속경막외수주진통용우관관절치환수술후노년병인적진통시안전적,효과학절,불량반응경.
Objective To evaluate the efficaey and safety of continuous epidural analgesia(CEA) with butorphanol in elderly patients undergoing hip replacement.Methods Sixty patients scheduled for selective hip replacement were randomized into group B (n=30) to receive patient-controlled epidural analgesia(PCEA) with butorphanol and group M (n=30) to receive PCEA with morphine.Their pain distribution at 5 time points,postoperative global score and the adverse effects in 48 h were observed.Results The pain distribution at the 5 time points or the global score for postoperative PCEA in 48 h showed no statistically significant difference between the two groups (P>0.05).Analgesia with butorphanol caused less adverse effects (respiratory depression,nausea and vomiting,itching and abdominal distension)than that with morphme(P<0.05).Conclusion CEA with butorphanol is safe and effective for the treatment of postoperative pain in elderly patients and causes less adverse effects than morphine.