CAJ | 학술논문

目的观察食管癌三维适形放疗的疗效及急性毒副反应.方法 28例食管癌患者接受三维适形放射治疗,处方剂量60～64 Gy/30～32次,200 Gy/次,1次/d,5次/周.评价疗效及急性毒副反应.结果全组完全缓解(CR)10例,部分缓解(PR)15例,无变化(NR)3例,总有效率(CR+PR)为89.3%;1、2年局部控制率和生存率分别为:75.0%,60.7%和71.4%,46.4%.急性放射性肺炎0级14例,1级8例,2级5例,3级1例;急性放射性食管炎0级5例,1级14例,2级7例,3级2例.结论三维适形放射治疗食管癌安全有效,能否提高远期生存率有待进一步观察.
목적 관찰식관암삼유괄형방료적료효급급성독부반응.방법 28례식관암환자접수삼유괄형방사치료,처방제량60～64 Gy/30～32차,200 Gy/차,1차/d,5차/주.평개료효급급성독부반응.결과 전조완전완해(CR)10례,부분완해(PR)15례,무변화(NR)3례,총유효솔(CR+PR)위89.3%;1、2년국부공제솔화생존솔분별위:75.0%,60.7%화71.4%,46.4%.급성방사성폐염0급14례,1급8례,2급5례,3급1례;급성방사성식관염0급5례,1급14례,2급7례,3급2례.결론 삼유괄형방사치료식관암안전유효,능부제고원기생존솔유대진일보관찰.
Objective To observe the curative effect of esophageal cancer with three-dimensional conformal radiotherapy and acute adverse reaction. Methods 28 cases with esophageal cancer were received three-dimensional conformal radiotherapy from August,2008 to August,2009. The conformal radiotherapy was performed in the way of 200cGy/fraction,5 fractions/week,total dose of 60-64Gy,30-32fraction. In addition,the curative effect and acute adverse reaction were evaluated along the radiotherapy. Results The number of complete relief(CR) cases was 10, part relief(PR) was 15 ,no change was 3 ,and the overall relief(CR + PR) rate was 89.3%. The local control rate and the survival rate in the first year were 75.0% and 60.7%, and second year were 71.4% and 46.4%. The cases of 0 level acute radioactive pneumonia was 14,1 level was 8,2 level was 5,3 level was 1. The cases of 0 level acute radioactive esophagitis was 5, 1 level was 14,2 level was 7,3 level was 2. Conclusion Three-dimensional conformal radiotherapy was a very safe and effective way to treat esophageal cancer. Whether the therapy could improve the long-term survival rate was remained to be observed.