实用妇产科杂志
實用婦產科雜誌
실용부산과잡지
JOURNAL OF PRACTICAL OBSTETRICS AND GYNECOLOGY
2010年
1期
30-32
,共3页
脐血管穿刺%产前诊断%染色体
臍血管穿刺%產前診斷%染色體
제혈관천자%산전진단%염색체
Percutaneous umbilical cord blood sampling%Prenatal diagnosis%Chromasomal abnormality
目的:评价超声引导下脐血管穿刺术在产前诊断中的应用,探讨胎儿染色体异常的临床高危因素,提高脐血管穿刺对胎儿异常染色体核型的检出率.方法:选取在我院超声引导下经腹脐血管穿刺并行染色体检查的孕妇283例,进行染色体核型分析,比较不同产前诊断指征组的异常染色体检出率及相关因素分析.结果:穿刺成功率100%,胎儿脐血管穿刺的主要并发症为穿刺点出血33例(11.66%),胎心心动过缓5例(1.77%).共检出异常染色体核型25例,检出率8.83%.发现夫妇中有染色体异常与胎儿染色体异常存在相关性(r=22.348,P=0.000).结论:超声引导下经腹脐血管穿刺抽取脐血在产前诊断中是较成熟有效的操作技术.夫妇双方有染色体异常是进行产前诊断的必要指征.
目的:評價超聲引導下臍血管穿刺術在產前診斷中的應用,探討胎兒染色體異常的臨床高危因素,提高臍血管穿刺對胎兒異常染色體覈型的檢齣率.方法:選取在我院超聲引導下經腹臍血管穿刺併行染色體檢查的孕婦283例,進行染色體覈型分析,比較不同產前診斷指徵組的異常染色體檢齣率及相關因素分析.結果:穿刺成功率100%,胎兒臍血管穿刺的主要併髮癥為穿刺點齣血33例(11.66%),胎心心動過緩5例(1.77%).共檢齣異常染色體覈型25例,檢齣率8.83%.髮現伕婦中有染色體異常與胎兒染色體異常存在相關性(r=22.348,P=0.000).結論:超聲引導下經腹臍血管穿刺抽取臍血在產前診斷中是較成熟有效的操作技術.伕婦雙方有染色體異常是進行產前診斷的必要指徵.
목적:평개초성인도하제혈관천자술재산전진단중적응용,탐토태인염색체이상적림상고위인소,제고제혈관천자대태인이상염색체핵형적검출솔.방법:선취재아원초성인도하경복제혈관천자병행염색체검사적잉부283례,진행염색체핵형분석,비교불동산전진단지정조적이상염색체검출솔급상관인소분석.결과:천자성공솔100%,태인제혈관천자적주요병발증위천자점출혈33례(11.66%),태심심동과완5례(1.77%).공검출이상염색체핵형25례,검출솔8.83%.발현부부중유염색체이상여태인염색체이상존재상관성(r=22.348,P=0.000).결론:초성인도하경복제혈관천자추취제혈재산전진단중시교성숙유효적조작기술.부부쌍방유염색체이상시진행산전진단적필요지정.
Objective:To evaluate the application of puncturing the umbilical cord under the ultrasound guidance in prenatal diagnosis,clinical high risk factors of fetal chromosomal abnormalities were discussed.Methods:283 pregnant women who had the percutaneous umbilical cord blood sampling were recruited and the karyotyping was done.The detection rate of chromosomal abnormalities and correlate factors in different subgroups of prenatal diagnosis were analyzed.Results:The success rate of puncture was 100%.Major complications were bleeing at the puncture site(33 cases,11.67%)and fetal heart brachycadia(5 cases,1.77%).25 chromosomal abnormalities were found and the detection rate was 8.83%.There was significant correlation between the couple's chromosomal abnormalities and the fetal's(r=22.348,P=0.000).Conclusions:The ultrasound guided percutaneous umbilical cord blood sampling proves to be valid in the prenatal diagnosis,especially when couples have chromosomal abnormalities.