CAJ | 학술논문

目的探讨药物自我处置程式对精神分裂症患者治疗依从性及社会功能的影响.方法将66例住院非急性期精神分裂症患者随机分为训练组(n=33)和对照组(n=33).在抗精神病药物治疗不变的前提下,训练组按药物自我处置程式进行分组训练8周.采用自制的药物依从性评分表和工作能力评分表、社会功能缺陷量表(SDSS)表对2组患者评估.结果训练组8周后及随访6个月治疗依从性、SDSS总分与对照组比较差异有显著性:治疗依从性(χ~2=9.188,29.630,P<0.01);SDSS总分[(2.63±2.74)分,(5.27±3.05)分,(1.69±2.35)分,(4.91±3.06)分,P=0.000];训练组随访6个月工作能力与对照组比较差异有显著性(χ~2=19.443,P=0.000).同组不同时点比较,训练组8周时患者治疗依从性(χ~2=8.053,P=0.018)、SDSS总分[(2.63±2.74)分,(6.81±3.06)分,P=0.000]较入组时有显著提高;2组随访6个月的治疗依从性均下降且与8周时有显著性差异(P<0.01).相关分析显示,患者SDSS总分在随访6个月时与治疗依从性及工作能力呈正相关.结论药物自我处置程式训练能提高患者的治疗依从性,改善其的社会功能和工作能力.
목적 탐토약물자아처치정식대정신분렬증환자치료의종성급사회공능적영향.방법장66례주원비급성기정신분렬증환자수궤분위훈련조(n=33)화대조조(n=33).재항정신병약물치료불변적전제하,훈련조안약물자아처치정식진행분조훈련8주.채용자제적약물의종성평분표화공작능력평분표、사회공능결함량표(SDSS)표대2조환자평고.결과 훈련조8주후급수방6개월치료의종성、SDSS총분여대조조비교차이유현저성:치료의종성(χ~2=9.188,29.630,P<0.01);SDSS총분[(2.63±2.74)분,(5.27±3.05)분,(1.69±2.35)분,(4.91±3.06)분,P=0.000];훈련조수방6개월공작능력여대조조비교차이유현저성(χ~2=19.443,P=0.000).동조불동시점비교,훈련조8주시환자치료의종성(χ~2=8.053,P=0.018)、SDSS총분[(2.63±2.74)분,(6.81±3.06)분,P=0.000]교입조시유현저제고;2조수방6개월적치료의종성균하강차여8주시유현저성차이(P<0.01).상관분석현시,환자SDSS총분재수방6개월시여치료의종성급공작능력정정상관.결론 약물자아처치정식훈련능제고환자적치료의종성,개선기적사회공능화공작능력.
Objective To explore the impact of medication self-management module on treatment compli-ance and social function of patients with schizophrenia. Methods 66 inpatients with schizophrenia in their non-acute stage were randomly divided into training group(n=33) and control group(n=33). Both groups received the anti-psychotics therapy. Medication self-management module was only given to the training group for 8 weeks.All subjects were follow up for 6 months and were evaluated with self-made drug treatment compliance rating scale,self-made work ability rating scale, social disability screening schedule(SDSS). Results Treatment compliance,the total scores of SDSS of training group were significantly higher than that of control group after 8 weeks and 6 months: treatment compliance (χ~2=9.188,29.630, P < 0.01); the total scores of SDSS ((2.63±2.74) vs (5.27 ±3.05), (1.69±2.35) vs (4.91±3.06), P=0.000); work ability of training group was significantly higher than that of control group after 6 months (χ~2=19.443, P=0.000). Treatment compliance (χ~2=8.053, P=0. 018), the total scores of SDSS((2.63±2.74) vs (6.81±3.06), P=0.000) of training group after 8 week and 6 months were significantly higher than that of pretraining. Treatment compliance and work ability of both groups on 6 months follow up were significantly lower than that of 8 weeks (P < 0.01). Correlation analysis can-firmed that there was positive relation between the total scores of SDSS and treatment compliance, work ability on 6 months later. Conclusion Medication self-management module could significantly improve treatment compliance,social function and work ability of patients with schizophrenia.