中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2008年
6期
25-26
,共2页
恶性滋养细胞肿瘤%彩色多普勒血流显像%诊断%化疗
噁性滋養細胞腫瘤%綵色多普勒血流顯像%診斷%化療
악성자양세포종류%채색다보륵혈류현상%진단%화료
Trophoblastic tumor malignant%Color Doppler flow imaging%Diagnosis%Chemotherapy
目的 应用彩色多普勒血流显像(CDFI)分析恶性滋养细胞肿瘤的血供类型特征,探讨CDFI在恶性滋养细胞肿瘤早期诊断及化疗监测中的应用价值.方法 分析研究组58例恶性滋养细胞肿瘤的血管形态学CDFI改变,对其峰值血流速度及阻力指数进行了测定,定量测量血β-HCG水平监测化疗反应,对照组36例为葡萄胎清宫术后恢复正常患者.结果 恶性滋养细胞肿瘤血流图分为3型:弥漫型、血窦型及实质型.研究组58例获病理诊断18例,包括5例弥漫型及8例血窦型结果为恶性葡萄胎,5例实质型为绒毛膜癌.结论 不同类型血流图与血β-HCG、子宫血流动力学改变及化疗的反应相关性好.在基层医院应用CDFI不仅可对恶性滋养细胞肿瘤进行早期诊断,而且可用于观察化疗效果,判断疾病预后转归.
目的 應用綵色多普勒血流顯像(CDFI)分析噁性滋養細胞腫瘤的血供類型特徵,探討CDFI在噁性滋養細胞腫瘤早期診斷及化療鑑測中的應用價值.方法 分析研究組58例噁性滋養細胞腫瘤的血管形態學CDFI改變,對其峰值血流速度及阻力指數進行瞭測定,定量測量血β-HCG水平鑑測化療反應,對照組36例為葡萄胎清宮術後恢複正常患者.結果 噁性滋養細胞腫瘤血流圖分為3型:瀰漫型、血竇型及實質型.研究組58例穫病理診斷18例,包括5例瀰漫型及8例血竇型結果為噁性葡萄胎,5例實質型為絨毛膜癌.結論 不同類型血流圖與血β-HCG、子宮血流動力學改變及化療的反應相關性好.在基層醫院應用CDFI不僅可對噁性滋養細胞腫瘤進行早期診斷,而且可用于觀察化療效果,判斷疾病預後轉歸.
목적 응용채색다보륵혈류현상(CDFI)분석악성자양세포종류적혈공류형특정,탐토CDFI재악성자양세포종류조기진단급화료감측중적응용개치.방법 분석연구조58례악성자양세포종류적혈관형태학CDFI개변,대기봉치혈류속도급조력지수진행료측정,정량측량혈β-HCG수평감측화료반응,대조조36례위포도태청궁술후회복정상환자.결과 악성자양세포종류혈류도분위3형:미만형、혈두형급실질형.연구조58례획병리진단18례,포괄5례미만형급8례혈두형결과위악성포도태,5례실질형위융모막암.결론 불동류형혈류도여혈β-HCG、자궁혈류동역학개변급화료적반응상관성호.재기층의원응용CDFI불부가대악성자양세포종류진행조기진단,이차가용우관찰화료효과,판단질병예후전귀.
Objective The gestational trophoblastic tumors of blood flow supply were analysed with color doppler flow imaging (CDFI) ,to investigate the value of CDFI in early diagnosis and monitoring the response of chemotherapy of the gestational trophoblastic tumor. Methods CDFI was used in diagnosis of 58 patients with gestational trophoblastic tumors. The vascular morphologic manifestations were recorded, and the peak systolic velocity and resistance index of uterine artery were calculated. Serum β-human chorionic gonadotrop in (HCG) levels were measured periodically to monitor chemotherapy response. 36 uneventful post moles uterine were enrolled as controls. Results Histopathologic diagnosis was available for 18 lesions. They were invasive mole in 8 lacunars type and 5 diffuse type lesions,5 chorioearcinoma necrosis in compact type lesions. The gestational trophoblastic tumors were categorized as diffuse type, lacunars type, and compact type according to their vascular pattems. Conclusion Vascular morphologic patterns of gestational trophoblastic tumors correlated well with β-HCG levels, uterine hemodynamics and chemotherapy. CDFI are useful for early diagnosis of the gestational trophoblastil tumors, for evaluating chemotherapeutic results and disease prognosis.
