中华肝胆外科杂志
中華肝膽外科雜誌
중화간담외과잡지
CHINESE JOURNAL OF HEPATOBILIARY SURGERY
2008年
7期
477-479
,共3页
胆管肿瘤%根治性切除术%姑息性切除术%外引流手术
膽管腫瘤%根治性切除術%姑息性切除術%外引流手術
담관종류%근치성절제술%고식성절제술%외인류수술
Bile duct neoplasms%Radical resection%Palliative resection%External drainage
目的 探讨肝门部胆管癌不同手术方式的临床疗效.方法 对89例肝门部胆管癌病人的临床资料进行回顾性研究.按治疗方式分为3组:根治性切除组(n=23),姑息性切除组(n=44),外引流手术组(n=22).对3组病人术后并发症、生存率、生存质量进行比较.结果 根治组术后并发症高于引流组(P<0.05),其与姑息组比较无显著性差异(P>0.05),两组围手术期死亡率比较无显著性差异(P>0.05),1、2、3年生存率比较根治组显著高于其它两组(P<0.01),生存质量比较根治组显著性高于姑息组及引流组(P<0.01),姑息组生存质量又显著性高于引流组(P<0.01).结论 肝门部胆管癌根治性切除能提高远期生存率,同时能明显提高病人的生存质量,对不能根治切除的病人,应争取行姑息性切除,亦可延长生存时间,改善生存质量.
目的 探討肝門部膽管癌不同手術方式的臨床療效.方法 對89例肝門部膽管癌病人的臨床資料進行迴顧性研究.按治療方式分為3組:根治性切除組(n=23),姑息性切除組(n=44),外引流手術組(n=22).對3組病人術後併髮癥、生存率、生存質量進行比較.結果 根治組術後併髮癥高于引流組(P<0.05),其與姑息組比較無顯著性差異(P>0.05),兩組圍手術期死亡率比較無顯著性差異(P>0.05),1、2、3年生存率比較根治組顯著高于其它兩組(P<0.01),生存質量比較根治組顯著性高于姑息組及引流組(P<0.01),姑息組生存質量又顯著性高于引流組(P<0.01).結論 肝門部膽管癌根治性切除能提高遠期生存率,同時能明顯提高病人的生存質量,對不能根治切除的病人,應爭取行姑息性切除,亦可延長生存時間,改善生存質量.
목적 탐토간문부담관암불동수술방식적림상료효.방법 대89례간문부담관암병인적림상자료진행회고성연구.안치료방식분위3조:근치성절제조(n=23),고식성절제조(n=44),외인류수술조(n=22).대3조병인술후병발증、생존솔、생존질량진행비교.결과 근치조술후병발증고우인류조(P<0.05),기여고식조비교무현저성차이(P>0.05),량조위수술기사망솔비교무현저성차이(P>0.05),1、2、3년생존솔비교근치조현저고우기타량조(P<0.01),생존질량비교근치조현저성고우고식조급인류조(P<0.01),고식조생존질량우현저성고우인류조(P<0.01).결론 간문부담관암근치성절제능제고원기생존솔,동시능명현제고병인적생존질량,대불능근치절제적병인,응쟁취행고식성절제,역가연장생존시간,개선생존질량.
Objective To investigate the clinical effect of surgical treatment for hilar cholangio-carcinoma. Methods The clinical data of 89 patients with hilar cholangiocarcinoma surgically treated in our hospital were retrospectively analyzed. They were divided into 3 groups: radical resection(group A,n=23),palliative resection (group B,n=44) and external drainage operation (group C,n=22). Complications,operative mortality,survival rate and posttreatment quality of lire were compara-tively analyzed among the 3 groups. Results The rate of complications was significantly higher in group A than in group C (P<0.05). There was no marked difference in operative mortality between group A and group B (P>0.05). The 1-,2-and 3-year survival rates and scoring of quality of life were remarkably higher in group A than in other 2 groups (P<0. 001 and 0. 05). Conclusion Radical re-section of hilar cholangiocarcinoma can improve the long-term survival and significantly enhance quality of life of the patients after operation. For patients receiving unradical resection, palliative surgical man-agement can improve the long-term survival and enhance quality of life.
