国际皮肤性病学杂志
國際皮膚性病學雜誌
국제피부성병학잡지
INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
2011年
2期
106-108
,共3页
生殖支原体%抗药性%动物模型
生殖支原體%抗藥性%動物模型
생식지원체%항약성%동물모형
Mycoplasma genitalium%Drug resistance%Models,animal
生殖支原体是性传播疾病的病原体之一,与非淋菌性尿道炎及女性宫颈炎等疾病密切相关.诊断生殖支原体感染的方法主要有培养、分子生物学及血清学法.目前治疗生殖支原体感染主要是阿奇霉素,但已经出现耐阿奇霉素的生殖支原体临床菌株的报道.针对生殖支原体的治疗药物的药效学研究平台主要有药物敏感性体外实验和动物模型.
生殖支原體是性傳播疾病的病原體之一,與非淋菌性尿道炎及女性宮頸炎等疾病密切相關.診斷生殖支原體感染的方法主要有培養、分子生物學及血清學法.目前治療生殖支原體感染主要是阿奇黴素,但已經齣現耐阿奇黴素的生殖支原體臨床菌株的報道.針對生殖支原體的治療藥物的藥效學研究平檯主要有藥物敏感性體外實驗和動物模型.
생식지원체시성전파질병적병원체지일,여비림균성뇨도염급녀성궁경염등질병밀절상관.진단생식지원체감염적방법주요유배양、분자생물학급혈청학법.목전치료생식지원체감염주요시아기매소,단이경출현내아기매소적생식지원체림상균주적보도.침대생식지원체적치료약물적약효학연구평태주요유약물민감성체외실험화동물모형.
Mycoplasma genitalium (Mg), a pathogen of sexually transmitted disease, is closely related with nongonococcal urethritis and cervicitis. The diagnosis of Mg infection mainly depends on culture,molecular biological and serological methods. Mg infection is primarily treated with azithromycin, but there have been reports on the resistance of Mg to azithromycin. Pharmacodynamic research on antibiotics against Mg is mainly through in vitro drug susceptibility testing and animal model experiment.