中华肾脏病杂志
中華腎髒病雜誌
중화신장병잡지
2011年
5期
337-340
,共4页
张建江%史佩佩%张利果%陆凤霞%赵丽丽
張建江%史珮珮%張利果%陸鳳霞%趙麗麗
장건강%사패패%장리과%륙봉하%조려려
紫癜,过敏性%儿童%免疫球蛋白G%食物不耐受
紫癜,過敏性%兒童%免疫毬蛋白G%食物不耐受
자전,과민성%인동%면역구단백G%식물불내수
Purpura,Henoch-Sch(o)nlein%Children%IgG%Food intolerance
目的 探讨食物不耐受与儿童过敏性紫癜的相关性及不耐受食物禁食或轮替疗法对过敏性紫癜患儿的疗效.方法 ELISA法检测40例过敏性紫癜患儿血清14种食物特异性IgG浓度及相关生化指标,同时进行3个月不耐受食物禁食或轮替疗法,观察疗效.结果 过敏性紫癜息儿食物不耐受阳性率为92.5%,鸡蛋的阳性率最高,其次为西红柿、牛奶、鳕鱼等.食物不耐受种类在男女、城乡分布间差异无统计学意义(t=1.053,P=0.315;t=1.388,P=0.193),但不同年龄间差异有统计学意义(t=2.257,P=0.045).食物不耐受累计敏感度与血清IgG浓度无直线相关(t=0.793,P=0.445).紫癜性肾炎患儿食物不耐受与其肾脏病理中免疫复合物沉积无相关(r=-0.262,P=0.387).不耐受食物禁食或轮替疗法有效率为95%.结论 儿童过敏性紫癜的发生和食物不耐受有密切关系.不耐受食物中以鸡蛋最为多见.不耐受食物禁食或轮替疗法对大部分过敏性紫癜患儿有效.
目的 探討食物不耐受與兒童過敏性紫癜的相關性及不耐受食物禁食或輪替療法對過敏性紫癜患兒的療效.方法 ELISA法檢測40例過敏性紫癜患兒血清14種食物特異性IgG濃度及相關生化指標,同時進行3箇月不耐受食物禁食或輪替療法,觀察療效.結果 過敏性紫癜息兒食物不耐受暘性率為92.5%,鷄蛋的暘性率最高,其次為西紅柿、牛奶、鱈魚等.食物不耐受種類在男女、城鄉分佈間差異無統計學意義(t=1.053,P=0.315;t=1.388,P=0.193),但不同年齡間差異有統計學意義(t=2.257,P=0.045).食物不耐受纍計敏感度與血清IgG濃度無直線相關(t=0.793,P=0.445).紫癜性腎炎患兒食物不耐受與其腎髒病理中免疫複閤物沉積無相關(r=-0.262,P=0.387).不耐受食物禁食或輪替療法有效率為95%.結論 兒童過敏性紫癜的髮生和食物不耐受有密切關繫.不耐受食物中以鷄蛋最為多見.不耐受食物禁食或輪替療法對大部分過敏性紫癜患兒有效.
목적 탐토식물불내수여인동과민성자전적상관성급불내수식물금식혹륜체요법대과민성자전환인적료효.방법 ELISA법검측40례과민성자전환인혈청14충식물특이성IgG농도급상관생화지표,동시진행3개월불내수식물금식혹륜체요법,관찰료효.결과 과민성자전식인식물불내수양성솔위92.5%,계단적양성솔최고,기차위서홍시、우내、설어등.식물불내수충류재남녀、성향분포간차이무통계학의의(t=1.053,P=0.315;t=1.388,P=0.193),단불동년령간차이유통계학의의(t=2.257,P=0.045).식물불내수루계민감도여혈청IgG농도무직선상관(t=0.793,P=0.445).자전성신염환인식물불내수여기신장병리중면역복합물침적무상관(r=-0.262,P=0.387).불내수식물금식혹륜체요법유효솔위95%.결론 인동과민성자전적발생화식물불내수유밀절관계.불내수식물중이계단최위다견.불내수식물금식혹륜체요법대대부분과민성자전환인유효.
Objective To investigate the correlation between food intolerance and Henoch-Sch(o)nlein purpura (HSP) in children and the efficacy of food forbidden or alternative therapy. Methods The levels of IgG against several common food in serum obtained from 40 children with HSP were measured by ELISA. The efficacy of food forbidden or alternative food therapy was assessed after 3 months. Results Total positive rate of serum food-intolerant IgG antibodies in HSP children was 92.5%. Among these 14 intolerant foods, the positive percentage of egg was the highest (33.8%), followed by tomato (14.9%), milk (13.5%) and morrhua (12.2%). Significant differences of the sort and degree of food intolerance existed among different age groups (t=2.257, P=0.045), but not between boys and girls (t=1.053, P=0.315), city and countryside (t= 1.388, P=0.193). There was no linear correlation between total food intolerance and serum IgG level (t=0.793, P=0.445). Food intolerance had no direct relation to immune complex deposition in kidneys of HSP nephritis (r =-0.262, P =0.387). The efficacy of adjusting diet was 95% . Conclusions HSP is closely related to food intolerance. Egg is the most common intolerant food. Food forbidden or alternative therapy shows acceptable efficacy in the treatment of most Henoch-Sch(o)nlein purpura children.
