CAJ | 학술논문

目的:探讨原发性和继发性干燥综合征(Ss)的不同临床特点,指导临床的诊断和治疗.方法:回顾性分析67例干燥综合征患者的临床症状、实验室及辅助检查结果和治疗的异同.结果:67例患者中41例为原发性Ss,26例为继发性Ss.原发性Ss常以单一症状发病,猖獗龋发生率、角膜荧光染色阳性率、γ-球蛋白升高发生率均较高,肾脏损害以肾小管间质损害为主;继发性Ss大部分以复合症状起病.肾脏损害以肾小球损害为主,肺损害较原发性Ss更严重.结论:原发性与继发性Ss有不同的临床特点和实验室检查结果,临床上要注意两者的鉴别和治疗的选择.
목적:탐토원발성화계발성간조종합정(Ss)적불동림상특점,지도림상적진단화치료.방법:회고성분석67례간조종합정환자적림상증상、실험실급보조검사결과화치료적이동.결과:67례환자중41례위원발성Ss,26례위계발성Ss.원발성Ss상이단일증상발병,창궐우발생솔、각막형광염색양성솔、γ-구단백승고발생솔균교고,신장손해이신소관간질손해위주;계발성Ss대부분이복합증상기병.신장손해이신소구손해위주,폐손해교원발성Ss경엄중.결론:원발성여계발성Ss유불동적림상특점화실험실검사결과,림상상요주의량자적감별화치료적선택.
Objective:To study the different clinical characteristics of primary and secondary Sjogren's syndrome(Ss)pa-tients.Methods:A retrospective study was performed on 67 patients with primary Ss(41 cases)and secondary Ss(26 cases).Results:There was a disparity between primary Ss and secondary Ss.The primary Ss often began with a single symptom,while secondary Ss with multiple symptoms,which is lack of specificity.Renal injury was one of the main symptoms in Ss.Tubular lesions were mole often in primary Ss,while renal glomerulus impairment was more frequent in secondary Ss.Pul-monary lesions were worse in secondary Ss.The incidences of hyper-gammaglobulinemia was more often in primary Ss.Con-clusions:The primary Ss was distinct from the secondary Ss in many respects.It is important to differentiate them and choose the right therapeutic regimens.