心血管病学进展
心血管病學進展
심혈관병학진전
ADVANCES IN CARDIOVASCULAR DISEASES
2010年
2期
273-275
,共3页
晚期糖基化终产物受体%动脉粥样硬化%高血压%糖尿病心肌病%心力衰竭
晚期糖基化終產物受體%動脈粥樣硬化%高血壓%糖尿病心肌病%心力衰竭
만기당기화종산물수체%동맥죽양경화%고혈압%당뇨병심기병%심력쇠갈
receptor for advanced glycation end products%atherosclerosis%hypertension%diabetic myocardiopathy%heart failure
晚期糖基化终产物受体属于细胞表面分子免疫球蛋白超家族中的一个新成员,可与多种配体结合后影响细胞内信号传导、刺激细胞因子释放等从而发挥其生物学效应.已知晚期糖基化终产物受体在糖尿病并发症、心血管疾病、神经系统疾病、肿瘤等疾病中起重要作用.现主要综述其在心血管疾病中的作用.
晚期糖基化終產物受體屬于細胞錶麵分子免疫毬蛋白超傢族中的一箇新成員,可與多種配體結閤後影響細胞內信號傳導、刺激細胞因子釋放等從而髮揮其生物學效應.已知晚期糖基化終產物受體在糖尿病併髮癥、心血管疾病、神經繫統疾病、腫瘤等疾病中起重要作用.現主要綜述其在心血管疾病中的作用.
만기당기화종산물수체속우세포표면분자면역구단백초가족중적일개신성원,가여다충배체결합후영향세포내신호전도、자격세포인자석방등종이발휘기생물학효응.이지만기당기화종산물수체재당뇨병병발증、심혈관질병、신경계통질병、종류등질병중기중요작용.현주요종술기재심혈관질병중적작용.
The receptor for advanced glycation endproducts is a member of the immunoglobulin superfamily.The receptor for advanced glycation endproducts binds to multiple ligands and exerts its effects by affecting intracellular signal transduction and stimulating the secretion of cytokines.The receptor for advanced glycation endproducts plays an important role in diabetic complications,cardiovascular diseases,neurological diseases,tumors,and more.This review focuses on its influence on cardiovascular diseases.
