CAJ | 학술논문

目的观察局部注射转移因子治疗糜烂型口腔扁平苔藓的临床疗效.方法口腔扁平苔藓患者100例,随机分为对照组(40例)和观察组(60例).对照组使用常规治疗方法,观察组基础治疗方法同对照组,同时黏膜下局部注射转移因子.结果观察组治疗后痊愈率、总有效率分别为51.7％、93.3％,均显著高于对照组的37.5％、80.0％；复发率5.0％(3/60),显著低于对照组的12.5％(5/40)(x2=9.23、5.78、6.30,均P＜0.05)；两组不良反应差异无统计学意义(P＞0.05).结论局部注射转移因子治疗糜烂型口腔扁平苔藓的疗效显著优于常规治疗方法,且不增加不良反应.
목적 관찰국부주사전이인자치료미란형구강편평태선적림상료효.방법 구강편평태선환자100례,수궤분위대조조(40례)화관찰조(60례).대조조사용상규치료방법,관찰조기출치료방법동대조조,동시점막하국부주사전이인자.결과 관찰조치료후전유솔、총유효솔분별위51.7％、93.3％,균현저고우대조조적37.5％、80.0％；복발솔5.0％(3/60),현저저우대조조적12.5％(5/40)(x2=9.23、5.78、6.30,균P＜0.05)；량조불량반응차이무통계학의의(P＞0.05).결론 국부주사전이인자치료미란형구강편평태선적료효현저우우상규치료방법,차불증가불량반응.
Objective To analyze the clinical effect of transfer factor( TF) local injection in the treatment of erosive oral lichen planus.Methods 100 patients with oral lichen planus were randomly divided in to the control group (40 cases) and the observation group(60 cases).The control group was given conventional treatment.The observation group was taken submucoeal local injection of TF on the basis of the control group.The clinical efficacy of the two groups and the adverse reaction of the courses were compared.Results The cure rate,the total effective rate of the observation group after treatment were 51.7％,93.3％,which were significantly higher than the control group of 37.5 ％,80.0％.The recurrence rate was 5.0％ (3/60),which was significantly lower than the control group 12.5 ％(5/40)(P＜0.05).There was no significant difference for the two sets of adverse reactions(P ＞0.05).Conclusion Local injection of TF in the treatment of erosive oral lichen planus was significantly better than conventional therapy,and it doesn't increase the adverse reactions.