CAJ | 학술논문

在灵芝基础培养基中添加小球藻粉,灵芝能对小球藻细胞进行生物破壁,同时进行生物转化.藻粉添加量以10g/L为最佳,产生的多糖最高达0.29mg/L.提取转化的多糖,并与灵芝多糖、小球藻提取多糖的混合物进行抗肿瘤实验.结果表明,产生的转化多糖抗肿瘤效果最好,在最适剂量(0.2g/kg · d )时,抑瘤率为76.2%.
재령지기출배양기중첨가소구조분,령지능대소구조세포진행생물파벽,동시진행생물전화.조분첨가량이10g/L위최가,산생적다당최고체0.29mg/L.제취전화적다당,병여령지다당、소구조제취다당적혼합물진행항종류실험.결과표명,산생적전화다당항종류효과최호,재최괄제량(0.2g/kg · d )시,억류솔위76.2%.
Appending Chlorella pyrenoidosa powder by 10g/L in the basic medium of Ganoderma lucidum could enhance the polysaccharides yield to 0. 29mg/L by bioconversion. In order to study the anti-tumor activity of different polysaccharides (from fermentation liquid of bioconverted Chlorella pyrenoidosa by Ganoderma lucidum, from fermentation liquid of Ganoderma lucidum in basic madium, from Chlorella pyrenoidosa, or mixed polysaccharides), an experiment was carried out in vivo. The results showed the bioconverted polysaccharides had the best anti-tumor activity. The anti-tumor inhibition was 76. 2% at the optimum