国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2012年
13期
985-987
,共3页
邱志辉%罗嘉莹%严惠婵%伍颖欣
邱誌輝%囉嘉瑩%嚴惠嬋%伍穎訢
구지휘%라가형%엄혜선%오영흔
阻塞性睡眠呼吸暂停%肥胖%低氧血症
阻塞性睡眠呼吸暫停%肥胖%低氧血癥
조새성수면호흡잠정%비반%저양혈증
Obstructive sleep apnea%Obesity%Hypoxemia
目的 探讨阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)患者体质量指数(BMI)与夜间低氧血症的关系.方法 回顾性分析1 899例经多导睡眠图(PSG)检查确诊为OSA患者(年龄为21～80岁),根据OSA患者BMI分正常体质量组(18.5 kg/m2≤BMI≤24 kg/m2)、超重组( 24 kg/m2＜BMI≤28 kg/m2)和肥胖组(BMI＞28 kg/m2),分析OSA患者的BMI、年龄与血氧饱和度＜90％时间占总睡眠时间百分比(TS90％)的相关性,比较不同体质量组OSA患者的TS90％差异.结果 OSA患者夜间TS90％与BMI呈正相关(r=0.421,P＜0.05),与年龄呈负相关(r=-0.087,P＜0.05).在年龄和AHI相似的情况下,其TS90％随着BMI的增加而加重,正常体质量组、超重组和肥胖组TS90％分别为(9.3±12.5)％、(10.0±10.0)％和(13.8±14.4)％,三组间差异有统计学意义(F =13,330,P=0.000).结论 伴有肥胖的OSA患者将加重夜间的低氧血症.
目的 探討阻塞性睡眠呼吸暫停(obstructive sleep apnea,OSA)患者體質量指數(BMI)與夜間低氧血癥的關繫.方法 迴顧性分析1 899例經多導睡眠圖(PSG)檢查確診為OSA患者(年齡為21～80歲),根據OSA患者BMI分正常體質量組(18.5 kg/m2≤BMI≤24 kg/m2)、超重組( 24 kg/m2＜BMI≤28 kg/m2)和肥胖組(BMI＞28 kg/m2),分析OSA患者的BMI、年齡與血氧飽和度＜90％時間佔總睡眠時間百分比(TS90％)的相關性,比較不同體質量組OSA患者的TS90％差異.結果 OSA患者夜間TS90％與BMI呈正相關(r=0.421,P＜0.05),與年齡呈負相關(r=-0.087,P＜0.05).在年齡和AHI相似的情況下,其TS90％隨著BMI的增加而加重,正常體質量組、超重組和肥胖組TS90％分彆為(9.3±12.5)％、(10.0±10.0)％和(13.8±14.4)％,三組間差異有統計學意義(F =13,330,P=0.000).結論 伴有肥胖的OSA患者將加重夜間的低氧血癥.
목적 탐토조새성수면호흡잠정(obstructive sleep apnea,OSA)환자체질량지수(BMI)여야간저양혈증적관계.방법 회고성분석1 899례경다도수면도(PSG)검사학진위OSA환자(년령위21～80세),근거OSA환자BMI분정상체질량조(18.5 kg/m2≤BMI≤24 kg/m2)、초중조( 24 kg/m2＜BMI≤28 kg/m2)화비반조(BMI＞28 kg/m2),분석OSA환자적BMI、년령여혈양포화도＜90％시간점총수면시간백분비(TS90％)적상관성,비교불동체질량조OSA환자적TS90％차이.결과 OSA환자야간TS90％여BMI정정상관(r=0.421,P＜0.05),여년령정부상관(r=-0.087,P＜0.05).재년령화AHI상사적정황하,기TS90％수착BMI적증가이가중,정상체질량조、초중조화비반조TS90％분별위(9.3±12.5)％、(10.0±10.0)％화(13.8±14.4)％,삼조간차이유통계학의의(F =13,330,P=0.000).결론 반유비반적OSA환자장가중야간적저양혈증.
Objective Obesity' s association with obstructive sleep apnea (OSA) is well established.The aim of this study was to examine the relation between body mass index (BMI) and nocturnal hypoxemia in patients with OSA.Methods We retrospectively studied 1 899 patients aged 21-80 years who underwent whole night polysomnography (PSG) during 2005-2011 were included in the study.The relationship between percentage of the duration of SaO2 below 90％ to total sleep time (TS90％) and BMI,age was analyzed.The subjects were divided into three groups based on their BMI:group normal ( 18.5 kg/m2 ≤ BMI≤ 24 kg/m2 ),group overweight (24 kg/m2 ＜ BMI≤ 28 kg/m2 ) and group obese (BMI ＞ 28 kg/m2 ).The nocturnal hypoxemia were compared between groups.Results TS90％ was positively correlated with BMI ( r =0.421,P ＜0.05),and age was negative correlated with TS90％ ( r =-0.087,P ＜0.05).Significant difference in TS90％ between groups ( F =13.330,P ＜0.05)and the TS90 ％ for group normal,group overweight and group obese were (9.3 ± 12.5) ％,( 10.0 ±10.0) ％ and (13.8 + 14.4)％ respectively.Conclusions Our results indicate that obesity lead to the deterioration of nocturnal hypoxemia in OSA.
