CAJ | 학술논문

目的探讨长期无创正压通气在稳定期慢性阻塞性肺疾病(COPD)患者中的应用价值.方法将符合条件的54例稳定期重度COPD患者分为治疗组和对照组,每组各27例,治疗组在一般治疗的同时给予长期无创正压通气治疗,对照组只接受一般治疗,所有治疗组和对照组患者在入组时(治疗前)及在治疗观察12周后(治疗后)两次进行测定BODE指数,并对所获结果进行统计学分析.结果治疗组患者治疗后较治疗前的BODE指数明显降低(P＜0.05)、呼吸困难评分显著改善(P＜0.05)、6分钟步行距离有极显著的提高(P＜0.01),BMI和FEV1有所改善,但差异无统计学意义(P＞0.05).对照组观察前后上述指标均无改善.结论长期无创正压通气可有效降低重度COPD患者的BODE指数,改善患者的临床症状及预后.
목적 탐토장기무창정압통기재은정기만성조새성폐질병(COPD)환자중적응용개치.방법 장부합조건적54례은정기중도COPD환자분위치료조화대조조,매조각27례,치료조재일반치료적동시급여장기무창정압통기치료,대조조지접수일반치료,소유치료조화대조조환자재입조시(치료전)급재치료관찰12주후(치료후)량차진행측정BODE지수,병대소획결과진행통계학분석.결과 치료조환자치료후교치료전적BODE지수명현강저(P＜0.05)、호흡곤난평분현저개선(P＜0.05)、6분종보행거리유겁현저적제고(P＜0.01),BMI화FEV1유소개선,단차이무통계학의의(P＞0.05).대조조관찰전후상술지표균무개선.결론 장기무창정압통기가유효강저중도COPD환자적BODE지수,개선환자적림상증상급예후.
Objective To evaluate the application value of long term non-invasive positive pressure ventilation in stable COPD patients.Methods Collect cases of 54 patients who have been diagnosed as COPD in stable period and are in accordance with the requirements of our study,and they were randomly divided into treatment and control groups,27 patients in each group.The treatment group was given general treatment and long term non-invasive positive pressure ventilation,and the control group was given simple general treatment.The BODE index was measured respectively before and after 12 weeks treatment in all patients of both groups.The results of experimental and control groups before and after treatment were statistically analyzed.Results The BODE index and MMRC significantly decreased after treatment in treatment group (P＜0.05),6MWD increased markedly in treatment group (P＜0.01).There was an improvement in BMI and FEV1,but this was not statistically significant (P＞0.05).No marked change of all above-mentioned indexes (BODE index,MMRC,6MWD,BMI and FEV1) was observed in control groups.Conclusions.Long term non-invasive positive pressure ventilation can effectively reduce the BODE index of sever COPD patients and improve their clinical symptom and prognosis.