CAJ | 학술논문

首先将辛基酚聚氧乙烯醚(OP10)、苯乙烯基酚聚氧乙烯醚(602)和蓖麻油聚氧乙烯(40)醚(EL-40)分别与蓖麻油聚氧乙烯(20)醚(EL-20)复配制备阿维菌素水乳剂,从亲水亲油平衡(HLB)值、临界胶束浓度(cmc)、表面张力等方面分析了二元表面活性剂复配对乳液稳定性的影响;其次,在EL-40与EL-20复配基础上,将苯乙烯基酚聚氧乙烯聚氧丙烯醚(1601),嵌段共聚物(L64)和辛基酚聚氧乙烯醚磷酸酯(A)分别添加到乳液中,从粒径、表面张力和zeta电势等方面考察三元表面活性剂复配对乳液稳定性的影响.结果表明:EL-40与EL-20复配具有较低的表面张力,可制备较稳定的乳液.添加1601和L64对乳液稳定性有一定提高;而添加A大大提高了乳液的稳定性,这是由于A显著降低了液滴粒径和表面张力,增加了zeta电势.
수선장신기분취양을희미(OP10)、분을희기분취양을희미(602)화비마유취양을희(40)미(EL-40)분별여비마유취양을희(20)미(EL-20)복배제비아유균소수유제,종친수친유평형(HLB)치、림계효속농도(cmc)、표면장력등방면분석료이원표면활성제복배대유액은정성적영향;기차,재EL-40여EL-20복배기출상,장분을희기분취양을희취양병희미(1601),감단공취물(L64)화신기분취양을희미린산지(A)분별첨가도유액중,종립경、표면장력화zeta전세등방면고찰삼원표면활성제복배대유액은정성적영향.결과표명:EL-40여EL-20복배구유교저적표면장력,가제비교은정적유액.첨가1601화L64대유액은정성유일정제고;이첨가A대대제고료유액적은정성,저시유우A현저강저료액적립경화표면장력,증가료zeta전세.
The preparation of avermyctin emulsions in water was achieved by mixing the surfactants polyoxyethylene (10) octylphenyl ether (OP10), polyoxyethylene styrenated phenol ether (602), and polyoxyethylene (40) castor oil ether (EL-40) with polyoxyethylene (20) castor oil ether (EL-20), separatively. Emulsion stability was investigated by analyzing the hydrophile-lipophile balance (HLB), critical micelle concentration (cmc), and surface tension. Then, the surfactants of polyoxyethylene polyoxypropylene styrenated phenol ether (1601), block copolymer (L64), and octyl phenyl polyoxyethylene phosphonate (A) were added to the emulsion made by blending EL-40 and EL-20, separatively. The stability of the emulsions was investigated further and discussed in terms of droplet size, surface tension, and zeta potential. Results showed that the blend of EL-40 and EL-20 resulted in a relatively stable emulsion because of its lower surface tension. The addition of 1601 and L64 improved the stability of the emulsion to some extent, while A greatly enhanced the stability because it markedly decreased the droplet size and the surface tension while increased the zeta potential.