CAJ | 학술논문

本文对17例正常小儿和16例恶性实体瘤患儿的外周血淋巴细胞中自然杀伤细胞活性进行了检测.结果表明恶性肿瘤患儿的自然杀伤细胞活性较正常小儿的明显降低(P＜0.05).此外,作者还发现化疗和手术对患儿自然杀伤细胞活性影响不大.
본문대17례정상소인화16례악성실체류환인적외주혈림파세포중자연살상세포활성진행료검측.결과표명악성종류환인적자연살상세포활성교정상소인적명현강저(P＜0.05).차외,작자환발현화료화수술대환인자연살상세포활성영향불대.
The NK activity of peripheral blood lymphocytes from 17 healthy and 16 malignant solid tumor-bearing children were determined and analysed with 125 IUdR release assay,The result Shows that no significant difference of NK activity has been discovered among the three age groups(<2 years,2 to 7 years and>7 years old)of pormal children. The mean value of NK activity is much lower than that of healthy adults. There is also no statistical difference of NK activity between the sex of healthy children. Compared with the normal ones,children with malignancy have obvious NK activity. The various stages of neuroblastoma have no relation to the NK activity, It indicates that chemotherapy and operative treatment have little effect on the NK activity.