中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
1期
54-56
,共3页
欧阳敏%范婵娟%王辉%白启轩%于久飞
歐暘敏%範嬋娟%王輝%白啟軒%于久飛
구양민%범선연%왕휘%백계헌%우구비
肿瘤相关性贫血%血清铁%铁蛋白%前白蛋白
腫瘤相關性貧血%血清鐵%鐵蛋白%前白蛋白
종류상관성빈혈%혈청철%철단백%전백단백
Tumor associated anemia%Serum iron%Serum ferritin%Serum prealbumin
目的 分析实体肿瘤患者贫血发生情况、贫血类型、铁代谢状况、前白蛋白水平的变化情况及其之间的相关性.方法 对2007年7月至2010年4月期间我院收治的370例恶性实体肿瘤患者的临床资料进行回顾性分析.结果 370例肿瘤患者中有206例存在贫血,发生率55.67%(206/370),其中轻度贫血129例,中、重度贫血77例,后者血清铁明显降低[(8.37±6.09)μmol/L];血清铁蛋白增高[(474.57±327.58)μg/L];血清铁降低与贫血程度有相关性(P＜0.05),而不同程度贫血之间血清铁蛋白差异无统计学意义(P＞0.05);所有贫血患者中,前白蛋白下降187例(90.77%),贫血下降的程度与前白蛋白下降未显示有相关性(P＞0.05).结论 恶性实体肿瘤患者贫血发生率较高,而且以正细胞正色素性贫血为主,与铁代谢障碍有关,与前白蛋白水平无相关性.
目的 分析實體腫瘤患者貧血髮生情況、貧血類型、鐵代謝狀況、前白蛋白水平的變化情況及其之間的相關性.方法 對2007年7月至2010年4月期間我院收治的370例噁性實體腫瘤患者的臨床資料進行迴顧性分析.結果 370例腫瘤患者中有206例存在貧血,髮生率55.67%(206/370),其中輕度貧血129例,中、重度貧血77例,後者血清鐵明顯降低[(8.37±6.09)μmol/L];血清鐵蛋白增高[(474.57±327.58)μg/L];血清鐵降低與貧血程度有相關性(P＜0.05),而不同程度貧血之間血清鐵蛋白差異無統計學意義(P＞0.05);所有貧血患者中,前白蛋白下降187例(90.77%),貧血下降的程度與前白蛋白下降未顯示有相關性(P＞0.05).結論 噁性實體腫瘤患者貧血髮生率較高,而且以正細胞正色素性貧血為主,與鐵代謝障礙有關,與前白蛋白水平無相關性.
목적 분석실체종류환자빈혈발생정황、빈혈류형、철대사상황、전백단백수평적변화정황급기지간적상관성.방법 대2007년7월지2010년4월기간아원수치적370례악성실체종류환자적림상자료진행회고성분석.결과 370례종류환자중유206례존재빈혈,발생솔55.67%(206/370),기중경도빈혈129례,중、중도빈혈77례,후자혈청철명현강저[(8.37±6.09)μmol/L];혈청철단백증고[(474.57±327.58)μg/L];혈청철강저여빈혈정도유상관성(P＜0.05),이불동정도빈혈지간혈청철단백차이무통계학의의(P＞0.05);소유빈혈환자중,전백단백하강187례(90.77%),빈혈하강적정도여전백단백하강미현시유상관성(P＞0.05).결론 악성실체종류환자빈혈발생솔교고,이차이정세포정색소성빈혈위주,여철대사장애유관,여전백단백수평무상관성.
Objective To explore the occurrence of anemia, anaemia type, iron metabolism situation,variation of serum Prealbumin (PA), and the relationship among them in cancer patients. Methods Three hundred and seventy cancer patients, admitted from July 2007 to April 2010 to our hospital, were enrolled into the study. The clinical data of all subjects were analyzed retrospectively. Results The incidence of anemia in 370 patients was 55.67% (206/370). Among all 206 anemia cases,129 cases had mild anaemia and 77 cases had middle to severe anaemia. In the last group ( n = 77 ), we found significant decrease in serum iron level ( [ 8. 37 ± 6. 09 ] μmol/L) and increase in serum ferritin level ( [ 474. 57 ± 327. 58 ] μg/L); and the correlation between serum iron and the anemia degree( Ps ＜ 0. 05 ). However, we found no significant differences of serum ferritin level between the groups with different degree of anemia(P ＞0. 05). Among all 206 anemia cases ,187(90. 77% ) patients had a low level of serum PA, but no relationship between the degree of anemia and the drop of serum PA ( P ＞ 0. 05 ). Conclusion The anemia was very popular in cancer patients, which had correlation with iron metabolism situation but not PA.
