中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
21期
2963-2965
,共3页
大肠肿瘤%肠梗阻%预后%影响因素
大腸腫瘤%腸梗阻%預後%影響因素
대장종류%장경조%예후%영향인소
Colorectal neoplasm%Intestinal obstruction%Prognosis%Influence factors
目的 分析手术治疗左半大肠癌并发急性肠梗阻的外科治疗效果及预后影响因素分析.方法 左半结肠癌并发急性肠梗阻患者70例,行一期切除吻合术65例,二期肠吻合术5例.结果 70例患者均治疗出院,术后并发症发生率为20.0%(14/70),病死率为1.0%(1/70);根治性手术后1、3、5年累积生存率分别为100.0%、93.6%、66.7%,高于姑息性手术的69.2%、0.0%、0.0%(均P＜0.01);单因素分析显示,肿瘤Dukes分期、肿瘤病理类型和化疗是影响左半大肠癌并梗阻术后生存率的重要因素(χ2=16.546、20.649、5.953,均P＜0.01);多因素分析显示,根治性手术是影响术后生存率的独立因素(Wald=5.877,P＜0.01).结论 一期根治手术治疗左半大肠癌并肠梗阻是可行的手术方式,可提高术后生存率.
目的 分析手術治療左半大腸癌併髮急性腸梗阻的外科治療效果及預後影響因素分析.方法 左半結腸癌併髮急性腸梗阻患者70例,行一期切除吻閤術65例,二期腸吻閤術5例.結果 70例患者均治療齣院,術後併髮癥髮生率為20.0%(14/70),病死率為1.0%(1/70);根治性手術後1、3、5年纍積生存率分彆為100.0%、93.6%、66.7%,高于姑息性手術的69.2%、0.0%、0.0%(均P＜0.01);單因素分析顯示,腫瘤Dukes分期、腫瘤病理類型和化療是影響左半大腸癌併梗阻術後生存率的重要因素(χ2=16.546、20.649、5.953,均P＜0.01);多因素分析顯示,根治性手術是影響術後生存率的獨立因素(Wald=5.877,P＜0.01).結論 一期根治手術治療左半大腸癌併腸梗阻是可行的手術方式,可提高術後生存率.
목적 분석수술치료좌반대장암병발급성장경조적외과치료효과급예후영향인소분석.방법 좌반결장암병발급성장경조환자70례,행일기절제문합술65례,이기장문합술5례.결과 70례환자균치료출원,술후병발증발생솔위20.0%(14/70),병사솔위1.0%(1/70);근치성수술후1、3、5년루적생존솔분별위100.0%、93.6%、66.7%,고우고식성수술적69.2%、0.0%、0.0%(균P＜0.01);단인소분석현시,종류Dukes분기、종류병리류형화화료시영향좌반대장암병경조술후생존솔적중요인소(χ2=16.546、20.649、5.953,균P＜0.01);다인소분석현시,근치성수술시영향술후생존솔적독립인소(Wald=5.877,P＜0.01).결론 일기근치수술치료좌반대장암병장경조시가행적수술방식,가제고술후생존솔.
Objective To investigate the effect of surgical treatment in left colorectal carcinoma with acute colorectal obstructive.Methods Clinical data of 70 patients with acute left obstructive colorectal carcinoma treated by emergent operation were collected.65 cases received one stage tumor resection and 5 cases received two stage tumor resection were retrospectively analyzed.Results The complication rate was 20.0%(14/70),mortality rate was 1.0%(1/70);radical surgery after 1,3,5-year cumulative survival rates were 100.0%,93.6%,66.7% wich were higher than the palliative surgery 69.2%,0.0%,0.0%(all P＜0.01);With univariate analysis,radical resection,Dukes stage,tumor differentiation,and chemotherapy were found to be significant factors associated with the overall survival(χ2 = 16.546,20.649,5.953,all P＜0.01);with the overall survival.With multivariate analysis,radical resection independently affected the overall survival(Wald = 5.877,P＜0.01).Conclusion One stage radical resection was feasible for left obstructive colorectal carcinoma,and could improve survival rate after operation.
