中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
4期
23-26
,共4页
高甘油三酯血症%急性胰腺炎%RANSON积分%诊断%治疗
高甘油三酯血癥%急性胰腺炎%RANSON積分%診斷%治療
고감유삼지혈증%급성이선염%RANSON적분%진단%치료
Hypertriglyceridemia%Acute pancreatitis%RANSON score%Diagnosis%Treatment
目的 研究高脂血症性急性胰腺炎(HLAP)的诊断及临床治疗措施.方法 回顾性分析比较2006年6月至2011年6月南阳市第二人民医院诊断的21例HLAP患者与同期42例非高脂血症性急性胰腺炎患者的临床资料,并对血甘油三酯(TG)值和RANSON积分进行相关分析.结果 与对照组相比,HLAP组男性居多,男女比例6∶1,平均年龄46.3岁,发病年龄较低；HLAP组TG、空腹血糖(GLU)、C-反应蛋白(CRP)、丙氨酸氨基转移(ALT)及天门冬氨酸氨基转移酶(AST)水平转氨酶均明显高于对照组.两组间比较差异均有统计学意义(P＜0.05).HLAP组RANSON积分平均值明显高于对照组(P＜0.05).63例AP的TG与RANSON积分存在显著相关性(P＜0.01).HLAP组中TG与RANSON积分的相关性更为显著(P＜0.01),其中尤以胆源性病例为甚.结论 高甘油三酯血症与AP的关系密切,血清甘油三酯水平与AP的病变程度呈正相关.AP患者合并高TG血症,则预示着病变程度可能加重、预后差.因此 AP患者应常规进行血脂的检测,做到早期诊断、早期治疗,以预防复发.
目的 研究高脂血癥性急性胰腺炎(HLAP)的診斷及臨床治療措施.方法 迴顧性分析比較2006年6月至2011年6月南暘市第二人民醫院診斷的21例HLAP患者與同期42例非高脂血癥性急性胰腺炎患者的臨床資料,併對血甘油三酯(TG)值和RANSON積分進行相關分析.結果 與對照組相比,HLAP組男性居多,男女比例6∶1,平均年齡46.3歲,髮病年齡較低；HLAP組TG、空腹血糖(GLU)、C-反應蛋白(CRP)、丙氨痠氨基轉移(ALT)及天門鼕氨痠氨基轉移酶(AST)水平轉氨酶均明顯高于對照組.兩組間比較差異均有統計學意義(P＜0.05).HLAP組RANSON積分平均值明顯高于對照組(P＜0.05).63例AP的TG與RANSON積分存在顯著相關性(P＜0.01).HLAP組中TG與RANSON積分的相關性更為顯著(P＜0.01),其中尤以膽源性病例為甚.結論 高甘油三酯血癥與AP的關繫密切,血清甘油三酯水平與AP的病變程度呈正相關.AP患者閤併高TG血癥,則預示著病變程度可能加重、預後差.因此 AP患者應常規進行血脂的檢測,做到早期診斷、早期治療,以預防複髮.
목적 연구고지혈증성급성이선염(HLAP)적진단급림상치료조시.방법 회고성분석비교2006년6월지2011년6월남양시제이인민의원진단적21례HLAP환자여동기42례비고지혈증성급성이선염환자적림상자료,병대혈감유삼지(TG)치화RANSON적분진행상관분석.결과 여대조조상비,HLAP조남성거다,남녀비례6∶1,평균년령46.3세,발병년령교저；HLAP조TG、공복혈당(GLU)、C-반응단백(CRP)、병안산안기전이(ALT)급천문동안산안기전이매(AST)수평전안매균명현고우대조조.량조간비교차이균유통계학의의(P＜0.05).HLAP조RANSON적분평균치명현고우대조조(P＜0.05).63례AP적TG여RANSON적분존재현저상관성(P＜0.01).HLAP조중TG여RANSON적분적상관성경위현저(P＜0.01),기중우이담원성병례위심.결론 고감유삼지혈증여AP적관계밀절,혈청감유삼지수평여AP적병변정도정정상관.AP환자합병고TG혈증,칙예시착병변정도가능가중、예후차.인차 AP환자응상규진행혈지적검측,주도조기진단、조기치료,이예방복발.
Objective To investigate the clinical diagnostic and therapeutic measures of hyperlipidemic acute pancreatitis(HLAP).Methods A retrospective study on the clinical data of 21 patients with HLAP was conducted in comparison with the data of 42 patients with non-HLAP during the period between Jun,2006 and Jun,2011.And the correlation between TG and RANSON score was analyzed.Results For patients with HLAP:six out of seven patients studied were male,with the average onset age being 46.3 years old.Compared with the non-HLAP group,the HLAP group had more male and younger patients,and the levels of TG,blood glucose,CRP,ALT and AST were evidently higher than those in the non-HLAP group.And there were significant differences between the two groups(P＜0.05).The RANSON score in HLAP group was obviously higher than that in non-HLAP group(P＜0.05).Furthermore,the correlation between TG and RANSON score in all the patients,especially in the HLAP group with acute biliaty pancreatitis(P＜0.01).Conclusions There is an close relationship between hypertriglyceridemia and acute pancreatitis,the high level of plasma TG plays a key role in acute pancreatitis,acute pancreatitis patients with hypertriglyceridemia are more likely to be severe and has poor prognosis.So early blood lipid test,diagnosis and treatment of HLAP should be carried out to prevent relapse of the disease.
