稀土
稀土
희토
CHINESE RARE EARTHS
2009年
6期
50-54
,共5页
杨自芳%何其庄%许东芳%沈智慧%沈敬一%夏庆春
楊自芳%何其莊%許東芳%瀋智慧%瀋敬一%夏慶春
양자방%하기장%허동방%침지혜%침경일%하경춘
稀土%壳聚糖%配合物%抑菌性能
稀土%殼聚糖%配閤物%抑菌性能
희토%각취당%배합물%억균성능
rare earth%chitosan%complexes%antibacterial properties
以天然高分子壳聚糖和稀土硝酸盐为原料,室温下,壳聚糖与稀土硝酸盐溶液在稀醋酸中反应,制得一系列新型稀土壳聚糖配合物.通过红外光谱、X射线能谱、差热-热重、X射线光电子能谱、透射电镜等对合成物进行分析、表征.所合成的配合物由分散的纳米粒子组成.并采用培养基扩散法、营养肉汤稀释法等抑菌实验方法对其进行了抑菌活性研究,结果表明其对大肠杆菌和金黄色葡萄球菌均有很好的抑菌作用,最小抑菌浓度(MIC)在200μg·mL~(-1)～300μg·mL~(-1)范围内,低于800μg·mL~(-1),且抑菌效果明显优于单独的壳聚糖、稀土硝酸盐.
以天然高分子殼聚糖和稀土硝痠鹽為原料,室溫下,殼聚糖與稀土硝痠鹽溶液在稀醋痠中反應,製得一繫列新型稀土殼聚糖配閤物.通過紅外光譜、X射線能譜、差熱-熱重、X射線光電子能譜、透射電鏡等對閤成物進行分析、錶徵.所閤成的配閤物由分散的納米粒子組成.併採用培養基擴散法、營養肉湯稀釋法等抑菌實驗方法對其進行瞭抑菌活性研究,結果錶明其對大腸桿菌和金黃色葡萄毬菌均有很好的抑菌作用,最小抑菌濃度(MIC)在200μg·mL~(-1)～300μg·mL~(-1)範圍內,低于800μg·mL~(-1),且抑菌效果明顯優于單獨的殼聚糖、稀土硝痠鹽.
이천연고분자각취당화희토초산염위원료,실온하,각취당여희토초산염용액재희작산중반응,제득일계렬신형희토각취당배합물.통과홍외광보、X사선능보、차열-열중、X사선광전자능보、투사전경등대합성물진행분석、표정.소합성적배합물유분산적납미입자조성.병채용배양기확산법、영양육탕희석법등억균실험방법대기진행료억균활성연구,결과표명기대대장간균화금황색포도구균균유흔호적억균작용,최소억균농도(MIC)재200μg·mL~(-1)～300μg·mL~(-1)범위내,저우800μg·mL~(-1),차억균효과명현우우단독적각취당、희토초산염.
The powder of rare earth chitosanwas prepared byusing the natural polymer-chitosan and rare earth nitratein dilute acetic acidand wascharacterized by FTIR,EDS,TG-DTA,XPS and TEM.The TEM image indicated that the compounds wereconsisted of dispersed particles with nano size. The antibacterial activity test showed that rare earth chitosan exhibited excellent antibacterial ability against Escherichia coli and Staphylococcus aureus. The minimum inhibitory concentration was about 200μg·mL~(-1)～300μg·mL~(-1). Rare earth chitosan distincted excelled individual chitosan andthe rare earth nitrate in antibacterial activity. The antimicrobial spectra of the compounds are broad.
