CAJ | 학술논문

瘦素是一种由肥胖基因编码、主要由脂肪组织合成和分泌的蛋白质,通过与其受体结合而发挥多种生物学效应.许多研究发现瘦素能减少脂肪蓄积,但其发挥作用的机制还不是很清楚.本文就瘦素对脂肪生成的作用,尤其是瘦素对前脂肪细胞增殖与分化的影响进行综述.
수소시일충유비반기인편마、주요유지방조직합성화분비적단백질,통과여기수체결합이발휘다충생물학효응.허다연구발현수소능감소지방축적,단기발휘작용적궤제환불시흔청초.본문취수소대지방생성적작용,우기시수소대전지방세포증식여분화적영향진행종술.
Leptin,the product of the obese gene,is a protein produced and secreted primarily by adipose tissue.Leptin initiates several biological effects by binding to its receptors.Many studies have shown that leptin can reduce fat accumulation,but its mechanism is still unclear.This article reviewed the effects of leptin on lipogenesis,and especially on proliferation and differentiation of preadipocytes.